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  1. No Access

    Article

    Expression of insulin-like factor 3 hormone-receptor system in the reproductive organs of male goats

    Relaxin-like factor (RLF), generally known as insulin-like factor 3 (INSL3), is essential for testis descent during fetal development. However, its role in adult males is not fully understood. We investigate t...

    Ali Mohammed Pitia, Itaru Minagawa, Naoto Uera, Koh-Ichi Hamano in Cell and Tissue Research (2015)

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    Article

    Role of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Predicting the Pathologic Response to Preoperative Chemoradiation Therapy in Patients With Resectable T3 Pancreatic Cancer

    The purpose of this study was to evaluate whether 18F-fluorodeoxyglucose positron emission tomography in combination with computed tomography (FDG-PET/CT) could correctly predict the pathologic response to preope...

    Hirotada Kittaka, Hidenori Takahashi, Hiroaki Ohigashi in World Journal of Surgery (2013)

  3. Article

    Open Access

    Loss of Maternal Annexin A5 Increases the Likelihood of Placental Platelet Thrombosis and Foetal Loss

    Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether endogenous Anxa5 prevents foeta...

    Hiroshi Ueki, Tomona Mizushina, Titaree Laoharatchatathanin in Scientific Reports (2012)

  4. Article

    Open Access

    Transforming growth factor beta family expression at the bovine feto-maternal interface

    Endometrial remodelling is necessary for implantation in all mammalian species. The TGF beta super-family plays a crucial role in this event in humans and mice. However, the role of TGF beta super-family membe...

    Kumiko Sugawara, Keiichiro Kizaki in Reproductive Biology and Endocrinology (2010)

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    Article

    Axillary Recurrence After Negative Sentinel Node Biopsy in a Patient with Breast Cancer: Report of a Case

    We report a case of axillary recurrence after sentinel node biopsy without axillary lymph node dissection in a patient with breast cancer. A hot and dye-stained node was identified at the primary operation and...

    Kazuyoshi Motomura, Chiyomi Egawa, Yoshifumi Komoike, Yoshihisa Hasegawa in Surgery Today (2006)

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    Article

    Controversies in sentinel node biopsy for breast cancer

    Sentinel node biopsy for breast cancer patients has recently been applied as a less invasive, highly accurate alternative to axillary lymph node dissection. Numerous studies have shown that sentinel nodes accu...

    Kazuyoshi Motomura, Yoshifumi Komoike, Sachiko Nagumo, Tsutomu Kasugai in Breast Cancer (2004)

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    Article

    Sentinel node biopsy to avoid axillary lymph node dissection in breast cancer

    The role of sentinel node biopsy in breast cancer has increased over the last few years. Sentinel nodes can predict the status of all axillary lymph nodes precisely and select patients with negative nodes for ...

    Kazuyoshi Motomura, Yoshifumi Komoike, Sachiko Nagumo, Tsutomu Kasugai in Breast Cancer (2002)

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    Chapter

    Two-Site Immunoassay for Native Inhibin A

    Inhibin is a glycoprotein consisting of two dissimilar subunits, termed α and β, that are linked by disulfide bonds (1–4). There are two β-subunit types: β A and β B. The α-subunit...

    Yoshihisa Hasegawa, Hiroo Madarame, Sintaro Yoshida in Inhibin, Activin and Follistatin (1997)

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    Chapter

    Evaluation of Maternal Serum Inhibin as a Marker for Complicated Pregnancy

    Inhibin is a gonadal glycoprotein hormone composed of two dissimilar disulfide-linked subunits that inhibits preferentially the secretion and production of follicle-stimulating hormone (FSH) (1,2). Recent stud...

    Hideki Mizunuma, Yoshihisa Hasegawa, Yumiko Abe in Inhibin, Activin and Follistatin (1997)

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    Article

    Effects of inhibin on activin A-Induced glucose metabolism in rat hepatocytes

    This study was conducted to investigate the effects of inhibin on hepatic glucose metabolism. We have previously reported that activin A induced a dose-dependent glycogenolytic action on hepatocytes, and that 10−...

    Tetsuya Mine, Hiroshi Yasuda, Toshiro Fujita, Yoshihisa Hasegawa in Endocrine (1996)

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    Article

    Analysis of factors affecting uptake of Tc-99m Sn-N-pyridoxyl-5-methyltryptophan by hepatocellular carcinoma

    We performed Tc-99m PMT imaging in 176 patients with HCC and evaluated factors affecting99mTc-PMT uptake by HCC with a logistic model. The probability of HCC showing increase in uptake of the radioisotope was 104...

    Yoshihisa Hasegawa, Shunichi Nakano, Tomotaka Sobue in Annals of Nuclear Medicine (1994)

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    Article

    Chromatographic and immunological identification of gonadotropin-releasing hormone in five marine teleosts

    Brain extracts from bluefin tuna, Thunnus thynnus, red seabream, Pagrus major, black seabream, Acanthopagrus schlegeli, red spotted grouper, Epinephelus akaara and Japanese flounder, Paralichthys olivaceus, were ...

    Koichi Okuzawa, Masafumi Amano, Katsumi Aida in Fish Physiology and Biochemistry (1993)

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    Article

    Changes in levels of GnRH in the brain and pituitary and GTH in the pituitary in male masu salmon, Oncorhynchus masou, from hatching to maturation

    Levels of two types of gonadotropin-releasing hormone (salmon GnRH and chicken GnRH-II) in the brain and pituitary, and content of gonadotropin (GTHIβ and IIβ) in the pituitary were measured in male masu salmo...

    Masafumi Amano, Katsumi Aida, Naoto Okumoto in Fish Physiology and Biochemistry (1993)

  14. No Access

    Chapter

    Role of Inhibins and Activins in Reproduction

    It is well established that mammalian reproduction is controlled by hypothalamic, pituitary, and gonadal hormones. Until recent years, steroid hormones had been considered the only known gonadal hormones. Howe...

    Masao Igarashi, Kaoru Miyamoto in Molecular Basis of Reproductive Endocrinol… (1993)

  15. No Access

    Article

    Localization of avian LHRH-immunoreactive neurons in the hypothalamus of the domestic fowl, Gallus domesticus, and the Japanese quail, Coturnix coturnix

    The localization of LHRH-containing perikarya and nerve fibers in the hypothalami of the domestic fowl and Japanese quail was investigated by means of the specific immunoperoxidase ABC method, using antisera a...

    Professor Shin-ichi Mikami, Shizuhiro Yamada in Cell and Tissue Research (1988)

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    Article

    Specific perfusion pattern in stress 201Tl myocardial scintigraphy of left main coronary artery disease

    The usefulness of stress 201Tl myocardial scintigraphy for identifying left main coronary artery disease was evaluated with data from 23 patients with 50% or more narrowing of the left main coronary artery and 56...

    Shigetoshi Wakasugi, Nobuhiko Shibata in European Journal of Nuclear Medicine (1986)