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  1. Article

    Open Access

    Practical initialization of the Nelder–Mead method for computationally expensive optimization problems

    Black-box optimization (BBO) algorithms are widely employed by practitioners to address computationally expensive real-world problems such as automatic tuning of machine learning models and evacuation route pl...

    Shintaro Takenaga, Yoshihiko Ozaki, Masaki Onishi in Optimization Letters (2023)

  2. Article

    Open Access

    Automated crystal structure analysis based on blackbox optimisation

    In the present study, we show that time-consuming manual tuning of parameters in the Rietveld method, one of the most frequently used crystal structure analysis methods in materials science, can be automated b...

    Yoshihiko Ozaki, Yuta Suzuki, Takafumi Hawai, Kotaro Saito in npj Computational Materials (2020)

  3. No Access

    Chapter and Conference Paper

    Speeding up of the Nelder-Mead Method by Data-Driven Speculative Execution

    The performance of machine learning algorithms considerably depends on the hyperparameter configurations. Previous studies reported that the Nelder-Mead (NM) method known as a local search method requires a sm...

    Shuhei Watanabe, Yoshihiko Ozaki, Yoshiaki Bando, Masaki Onishi in Pattern Recognition (2020)

  4. No Access

    Article

    Reactivation of intraabdominal tuberculous lymphadenopathy after drug-eluting beads transcatheter arterial chemoembolization in a patient with hepatocellular carcinoma

    Owing to effective treatments and sanitary improvements, the incidence of latent tuberculosis infection (LTBI) has decreased. However, approximately one-quarter of the world’s population is thought to have LTB...

    Yosuke Murata, Katsushi Hiramatsu, Yumi Yoshida in Clinical Journal of Gastroenterology (2019)

  5. Article

    Open Access

    Effective hyperparameter optimization using Nelder-Mead method in deep learning

    In deep learning, deep neural network (DNN) hyperparameters can severely affect network performance. Currently, such hyperparameters are frequently optimized by several methods, such as Bayesian optimization a...

    Yoshihiko Ozaki, Masaki Yano, Masaki Onishi in IPSJ Transactions on Computer Vision and A… (2017)

  6. No Access

    Article

    A case of protein-losing enteropathy caused by sclerosing mesenteritis diagnosed with capsule endoscopy and double-balloon endoscopy

    A 75-year-old man presented with abdominal distension, hypoproteinemia, ascites and a 35-mm mass in the small bowel mesentery. Laparotomy was performed, and he was diagnosed with sclerosing mesenteritis. His c...

    Yasushi Saito, Katsushi Hiramatsu, Takuto Nosaka in Clinical Journal of Gastroenterology (2017)

  7. Article

    Open Access

    Ruptured hepatic metastases of cutaneous melanoma during treatment with vemurafenib: an autopsy case report

    The spontaneous rupture of hepatic metastases is rare compared to that of primary hepatic tumors. In addition, vemurafenib, a selective inhibitor of the mutant BRAF protein or gene product, has been reported t...

    Takuto Nosaka, Katsushi Hiramatsu, Tomoyuki Nemoto, Yasushi Saito in BMC Clinical Pathology (2015)

  8. No Access

    Article

    A case of Helicobacter pylori-negative intramucosal well-differentiated gastric adenocarcinoma with intestinal phenotype

    A woman in her 30s visited our hospital with stool abnormality. Esophagogastroduodenoscopy revealed a depressed lesion on the greater curvature of the gastric antrum. The tumor was diagnosed as a well-differen...

    Yoshihiko Ozaki, Hiroyuki Suto, Takuto Nosaka in Clinical Journal of Gastroenterology (2015)

  9. No Access

    Chapter and Conference Paper

    MEMS Meets Insects

    We did not know suitable mechanisms or functions in microsystems when we obtained the fabrication technology to build Micro Electro Mechanical Systems (MEMS) for the first time. Consequently, the conventional ...

    Isao Shimoyama, Kazunori Hoshino, Yoshihiko Ozaki in Transducers ’01 Eurosensors XV (2001)