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Article
Open AccessPractical initialization of the Nelder–Mead method for computationally expensive optimization problems
Black-box optimization (BBO) algorithms are widely employed by practitioners to address computationally expensive real-world problems such as automatic tuning of machine learning models and evacuation route pl...
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Article
Open AccessAutomated crystal structure analysis based on blackbox optimisation
In the present study, we show that time-consuming manual tuning of parameters in the Rietveld method, one of the most frequently used crystal structure analysis methods in materials science, can be automated b...
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Chapter and Conference Paper
Speeding up of the Nelder-Mead Method by Data-Driven Speculative Execution
The performance of machine learning algorithms considerably depends on the hyperparameter configurations. Previous studies reported that the Nelder-Mead (NM) method known as a local search method requires a sm...
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Article
Reactivation of intraabdominal tuberculous lymphadenopathy after drug-eluting beads transcatheter arterial chemoembolization in a patient with hepatocellular carcinoma
Owing to effective treatments and sanitary improvements, the incidence of latent tuberculosis infection (LTBI) has decreased. However, approximately one-quarter of the world’s population is thought to have LTB...
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Article
Open AccessEffective hyperparameter optimization using Nelder-Mead method in deep learning
In deep learning, deep neural network (DNN) hyperparameters can severely affect network performance. Currently, such hyperparameters are frequently optimized by several methods, such as Bayesian optimization a...
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Article
A case of protein-losing enteropathy caused by sclerosing mesenteritis diagnosed with capsule endoscopy and double-balloon endoscopy
A 75-year-old man presented with abdominal distension, hypoproteinemia, ascites and a 35-mm mass in the small bowel mesentery. Laparotomy was performed, and he was diagnosed with sclerosing mesenteritis. His c...
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Article
Open AccessRuptured hepatic metastases of cutaneous melanoma during treatment with vemurafenib: an autopsy case report
The spontaneous rupture of hepatic metastases is rare compared to that of primary hepatic tumors. In addition, vemurafenib, a selective inhibitor of the mutant BRAF protein or gene product, has been reported t...
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Article
A case of Helicobacter pylori-negative intramucosal well-differentiated gastric adenocarcinoma with intestinal phenotype
A woman in her 30s visited our hospital with stool abnormality. Esophagogastroduodenoscopy revealed a depressed lesion on the greater curvature of the gastric antrum. The tumor was diagnosed as a well-differen...
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Chapter and Conference Paper
MEMS Meets Insects
We did not know suitable mechanisms or functions in microsystems when we obtained the fabrication technology to build Micro Electro Mechanical Systems (MEMS) for the first time. Consequently, the conventional ...