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  1. Article

    Open Access

    Successful surgical intervention for acute pyothorax caused by methicillin-resistant Staphylococcus aureus thoracic pyogenic spondylitis: a case report

    Pyogenic spondylitis or intervertebral discitis rarely spreads into the thoracic cavity, resulting in pyothorax. Moreover, no study has reported methicillin-resistant Staphylococcus aureus (MRSA) as a cause. Cons...

    Naoya Kitamura, Yoshifumi Shimada in General Thoracic and Cardiovascular Surger… (2024)

  2. No Access

    Article

    Deep learning-based prediction model for postoperative complications of cervical posterior longitudinal ligament ossification

    Postoperative complication prediction helps surgeons to inform and manage patient expectations. Deep learning, a model that finds patterns in large samples of data, outperform traditional statistical methods i...

    Sadayuki Ito, Hiroaki Nakashima, Toshitaka Yoshii, Satoru Egawa in European Spine Journal (2023)

  3. Article

    Open Access

    Comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: a multicenter study

    To evaluate the radiological differences between diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) using whole spine computed tomography (CT), including the spine and sacroiliac j...

    Takuya Takahashi, Toshitaka Yoshii, Kanji Mori, Shigeto Kobayashi in Scientific Reports (2023)

  4. Article

    Open Access

    Usefulness of modified S-line for upper instrumented vertebra selection in adolescent idiopathic scoliosis Lenke type 2 curves

    No validated systems exist for selecting the upper instrumented vertebra (UIV) for optimal postoperative shoulder balance in Lenke type 2 adolescent idiopathic scoliosis (AIS). This study evaluated a new metho...

    Tetsuhiko Mimura, Shota Ikegami, Tomohiro Banno, Shoji Seki in Scientific Reports (2022)

  5. Article

    Open Access

    A deep convolutional neural network to predict the curve progression of adolescent idiopathic scoliosis: a pilot study

    Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity that predominantly occurs in girls. While skeletal growth and maturation influence the development of AIS, accurate prediction of c...

    Yasuhito Yahara, Manami Tamura, Shoji Seki, Yohan Kondo in BMC Musculoskeletal Disorders (2022)

  6. Article

    Open Access

    Impact of obesity on cervical ossification of the posterior longitudinal ligament: a nationwide prospective study

    Positive association between ossification of the posterior longitudinal ligament of the spine (OPLL) and obesity is widely recognized; however, few studies focused on the effects of obesity on treatment of cer...

    Kanji Mori, Toshitaka Yoshii, Satoru Egawa, Kenichiro Sakai in Scientific Reports (2022)

  7. Article

    Open Access

    Efficacy of surgeon-directed postoperative local injection with an analgesic mixture in posterior fusion surgery for adolescent idiopathic scoliosis

    Severe postsurgical pain in posterior spinal fusion is common. Multimodality analgesia, including opioid-based patient-controlled analgesia (PCA), is commonly used, but opioid-related adverse events such as na...

    Hiroto Makino, Shoji Seki, Katsuhiko Kamei in BMC Musculoskeletal Disorders (2022)

  8. Article

    Open Access

    Comparison of laminoplasty and posterior fusion surgery for cervical ossification of posterior longitudinal ligament

    This prospective multicenter study, established by the Japanese Ministry of Health, Labour and Welfare and involving 27 institutions, aimed to compare postoperative outcomes between laminoplasty (LM) and poste...

    Hiroaki Nakashima, Shiro Imagama, Toshitaka Yoshii, Satoru Egawa in Scientific Reports (2022)

  9. No Access

    Chapter

    Cervical Spondylotic Myelopathy

    Cervical spondylotic myelopathy (CSM) is a degenerative condition secondary to cervical cord compression; symptoms are variable (clumsiness or a loss of fine motion skills in the hand, spastic gait, vesicouret...

    Yoshiharu Kawaguchi in Essentials of Spine Surgery (2022)

  10. No Access

    Chapter

    Thoracic Disk Herniation

    Thoracic disk herniation (TDH) can cause spinal cord compression due to the prolapse of the thoracic disk into the spinal canal; it is associated with numbness and symptoms of thoracic myelopathy (weakness of ...

    Yoshiharu Kawaguchi in Essentials of Spine Surgery (2022)

  11. Article

    Open Access

    The impact of ossification spread on cervical spine function in patients with ossification of the posterior longitudinal ligament

    Ossification of the posterior longitudinal ligament (OPLL) is a progressive disease. The bridging of ossified lesions to the vertebral body gradually increases, thereby decreasing the mobility of the cervical ...

    Keiichi Katsumi, Takashi Hirai, Toshitaka Yoshii, Satoshi Maki in Scientific Reports (2021)

  12. Article

    Open Access

    Neurological improvement is associated with neck pain attenuation after surgery for cervical ossification of the posterior longitudinal ligament

    Although favourable surgical outcomes for myelopathy caused by cervical ossification of the posterior longitudinal ligament (OPLL) have been reported, factors significantly associated with post-operative neck ...

    Masao Koda, Toshitaka Yoshii, Satoru Egawa, Kenichiro Sakai in Scientific Reports (2021)

  13. Article

    Open Access

    Clinical characteristics in patients with ossification of the posterior longitudinal ligament: A prospective multi-institutional cross-sectional study

    Ossification of the posterior longitudinal ligament (OPLL) can occur throughout the entire spine and can sometimes lead to spinal disorder. Although patients with OPLL sometimes develop physical limitations be...

    Takashi Hirai, Toshitaka Yoshii, Shuta Ushio, Kanji Mori in Scientific Reports (2020)

  14. Article

    Open Access

    Sacroiliac joint variation associated with diffuse idiopathic skeletal hyperostosis

    Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by the ossification of vertebral bodies and peripheral entheses. However, variations in sacroiliac (SI) joint change in patients with DISH have ...

    Yasuhito Yahara, Taketoshi Yasuda, Yoshiharu Kawaguchi in BMC Musculoskeletal Disorders (2020)

  15. No Access

    Chapter

    Open-Door Laminoplasty for Cervical OPLL: Technique, Long-Term Results, and Complications

    Cervical laminoplasty has become a standard procedure for the posterior decompression of the cervical cord, as ossification of the posterior longitudinal ligament (OPLL) a potential of cervical cord compressio...

    Yoshiharu Kawaguchi in OPLL (2020)

  16. No Access

    Chapter

    Evaluation of Distribution Patterns of Spinal Ligament Ossification Using Whole-Spine Computed Tomography in Patients with Cervical Ossification of the Posterior Longitudinal Ligament

    Ossification of the posterior longitudinal ligament (OPLL) and other types of spinal ligament ossification are common in Japan and are known to frequently cause neuropathy. Cervical OPLL is a common form of OP...

    Takashi Hirai, Toshitaka Yoshii, Atsushi Okawa, Yoshiharu Kawaguchi in OPLL (2020)

  17. No Access

    Article

    Sternum-splitting anterior approach following posterior decompression and fusion in patients with massive ossification of the posterior longitudinal ligament in the upper thoracic spine: report of 2 cases and literature review

    Anterior approach to the upper thoracic spine is difficult. It is important for spine surgeons to know the indication and the effect of anterior decompression for upper thoracic lesions and also to recognize t...

    Yoshiharu Kawaguchi, Shoji Seki, Yasuhito Yahara, Takahiro Homma in European Spine Journal (2018)

  18. Article

    Open Access

    Distribution of ossified spinal lesions in patients with severe ossification of the posterior longitudinal ligament and prediction of ossification at each segment based on the cervical OP index classification: a multicenter study (JOSL CT study)

    In patients with ossification of the posterior longitudinal ligament (OPLL) in the cervical spine, it is well known that the thoracic ossified lesions often coexist with the cervical lesions and can cause seve...

    Takashi Hirai, Toshitaka Yoshii, Narihito Nagoshi in BMC Musculoskeletal Disorders (2018)

  19. Article

    Open Access

    Clinical and imaging characteristics in patients undergoing surgery for lumbar epidural lipomatosis

    Lumbar epidural lipomatosis (LEL) is characterized by abnormal accumulation of unencapsulated adipose tissue in the spinal epidural space. Such accumulation compresses the dural sac and nerve roots, and result...

    Taketoshi Yasuda, Kayo Suzuki, Yoshiharu Kawaguchi in BMC Musculoskeletal Disorders (2018)

  20. Article

    Open Access

    A selective inhibition of c-Fos/activator protein-1 as a potential therapeutic target for intervertebral disc degeneration and associated pain

    Intervertebral disc (IVD) degeneration is a major cause of low back pain. The transcription factor c-Fos/Activator Protein-1 (AP-1) controls the expression of inflammatory cytokines and matrix metalloproteinas...

    Hiroto Makino, Shoji Seki, Yasuhito Yahara, Shunichi Shiozawa in Scientific Reports (2017)

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