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Article
Open AccessWhich Capital Flow Surge Methods Are Better at Predicting Reversals and Sudden Stops?: Balancing Type 1 and Type 2 Errors
Capital flow surges have become a major source of concern as they have been often followed by disruptive reversals and sudden stops. We introduce F-score methodology which evaluates how well particular capital...
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Article
A small molecule compound 759 inhibits the wnt/beta-catenin signaling pathway via increasing the Axin protein stability
Wnt/β-catenin signaling plays important role in cancers. Compound 759 is one of the compounds previously screened to identify inhibitors of the Wnt/β-catenin pathway in A549 cells [Lee et al. in Bioorg Med Che...
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Article
Highly efficient blue InGaN nanoscale light-emitting diodes
Indium gallium nitride (InGaN)-based micro-LEDs (μLEDs) are suitable for meeting ever-increasing demands for high-performance displays owing to their high efficiency, brightness and stability1–5. However, μLEDs h...
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Article
Open AccessAIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis
Recent development of the chemical inhibitors specific to oncogenic KRAS (Kirsten Rat Sarcoma 2 Viral Oncogene Homolog) mutants revives much interest to control KRAS-driven cancers. Here, we report that AIMP2-...
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Article
Open AccessThe disubstituted adamantyl derivative LW1564 inhibits the growth of cancer cells by targeting mitochondrial respiration and reducing hypoxia-inducible factor (HIF)-1α accumulation
Targeting cancer metabolism has emerged as an important cancer therapeutic strategy. Here, we describe the synthesis and biological evaluation of a novel class of hypoxia-inducible factor (HIF)-1α inhibitors, ...
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Article
Open AccessA novel pyrazole derivative protects from ovariectomy-induced osteoporosis through the inhibition of NADPH oxidase
Osteoclast cells (OCs) are differentiated from bone marrow-derived macrophages (BMMs) by activation of receptor activator of nuclear factor κB (NF-κB) ligand (RANKL). Activation of NADPH oxidase (Nox) isozymes...
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Chapter and Conference Paper
Protocol for a Simplified Processor-Memory Interface Using High-Speed Serial Link
In our work, the interface protocol between a processor and memory built using an optical connection is described. We designed a serial interface protocol to simplify a parallel interface between the processor...
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Article
Open AccessHistone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model
In light of the anti-inflammatory properties of histone deacetylase (HDAC) inhibitors, such as suberoylanilide hydroxamic acid (SAHA) and trichostatin A (TSA), we examined a new HDAC inhibitor KBH-A42 for its ...
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Article
Stereoselective synthesis of (E)- and (Z)-enol ethers from β-amino aldehydes
Stereocontrolled methods for the direct and divergent synthesis of the silylenol ethers possessing amino group from β-amino aldehydes have been achieved. These enol ethers with the defined olefin geometry coul...
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Article
Effect of crystallization on Adhesion Strength of External Electrode in LTCC
A mixture system of MO-SiO2 (M: Ca, Sr, Ba) glass and Al2O3 crystalline powder has been investigated as a substrate material for low temperature co-fired ceramics (LTCC). This type of glass-ceramic mixture is kno...
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Article
Cycle-Accurate Energy Measurement and Characterization of FPGAs
Field Programmable Gate Arrays (FPGAs) play many important roles, ranging from small glue logic replacement to System-on-Chip (SoC) designs. Nevertheless, FPGA vendors cannot accurately specify the power consu...
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Chapter and Conference Paper
Performance Improvement of DS/CDMA System under Impulsive Noise Environments
In this paper, we have evaluated the BER performance of an asynchronous DS/CDMA BPSK system using a conventional receiver under impulsive noise environments, and have proposed a selective hard limiting (SHL) r...
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Article
Synthesis and biological activity of 5-hydroxy-4-quinolones and 5-methoxy-4-quinolones as truncated acridones
A series of 5-hydroxy-4-quinolone (3) and 5-methoxy-4-quinolone (4) derivatives were synthesized as truncated acridone analogues and evaluated for antitumor, antiherpes and antituberculosis activities. Among them...
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Article
Current status of anti-HBV chemotherapy
In the past decade, significant progress has been achieved in the battle against hepatitis B virus. In addition to the immunomodulating agents such as interferon-α and thymosin, many novel antiviral agents hav...
