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Article
Dynamic mechanical properties of an ore rock with varying grade and engineering applications in mines
The dynamic mechanical properties of ore rock are important in blast designs and support designs for underground mines. However, few studies have focused on ore rock with varying grade, and the application of ...
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Article
Evaluation of safety and deformation characteristics of the secondary stope sandwiched between backfills in underground iron mines
In a large underground iron mine (over 2000, 000 t/a) in China, a large volume of mined void could not be filled in time, which posed a threat to the working face. Physical and numerical models were used to in...
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Article
Research and application of a comprehensive forecasting system for tunnels in water-bearing fault fracture zones: a case study
In the process of tunnel construction, there is a high probability of encountering fault fracture zones. Tunnel deformation, water-inrush, and mud-inrush accidents easily occur in these sections. There is an u...
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Article
Application and prospective of 3D printing in rock mechanics: A review
This review aims to discuss the application and development of three-dimensional printing (3DP) technology in the field of rock mechanics and the mechanical behaviors of 3D-printed specimens on the basis of va...
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Article
Fracture Characteristics of Orebody Rock with Varied Grade Under Dynamic Brazilian Tests
In mining engineering, the grade of the orebody significantly influences mining activities. Typically, the grade of completed mine sequences can be used to estimate the yearly mine’s production and profit. How...
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Article
Effect Mechanism of Fractures on the Mechanics Characteristics of Jointed Rock Mass Under Compression
Based on the theory of particle flow and the PFC2D program, a jointed rock mass model was constructed with a single-joint rock and angle joints of 0 ...
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Article
Open AccessUp-regulation of miR-370-3p restores glioblastoma multiforme sensitivity to temozolomide by influencing MGMT expression
MicroRNAs (miRNA) are believed to play an important role in glioblastoma multiforme (GBM)chemotherapy. Our study aims to investigate potential miRNA biomarkers in GBM. Sixty GBM patients, which were given temo...
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Article
Cisplatin targets the stromal cell-derived factor-1-CXC chemokine receptor type 4 axis to suppress metastasis and invasion of ovarian cancer-initiating cells
In ovarian cancer, CD44+/CD117+ stem cells, also known as cancer-initiating cells (CICs), are highly proliferative and invasive. Therefore, the CD44+/CD117+ subpopulation is thought to be an important target f...
