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    Article

    Human Prion Protein Mutants with Deleted and Inserted Octarepeats Undergo Different Pathways to Trigger Cell Apoptosis

    Octarepeats region sequence is one of the most important characteristics of PrP topology. To explore the mechanism of deleted and inserted octarepeats mutants PrP-caused apoptosis, wild-type PrP (PrP-PG5), and...

    Kun Xu, **n Wang, Qi Shi, Cao Chen, Chan Tian in Journal of Molecular Neuroscience (2011)

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    Article

    The correlations between HPV16 infection and expressions of c-erbB-2 and bcl-2 in breast carcinoma

    Breast carcinoma (BC) is a prevalent malignant tumour occurring in women. Many studies have indicated the role of human papilloma virus type 16 (HPV16) in the pathogenesis of BC; however, the correlations of H...

    Qian He, Shu-Qun Zhang, Yong-Lie Chu, **ao-Li Jia in Molecular Biology Reports (2009)

  3. Article

    Over-expression of nm23-H1 in HeLa cells provides cells with higher resistance to oxidative stress possibly due to raising intracellular p53 and GPX1

    To determine whether the antitumor factor nm23 is related with antioxidation.

    Run An, Yong-lie Chu, Chan Tian, **ao-xia Dai, **g-hong Chen in Acta Pharmacologica Sinica (2008)

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    Article

    T-2 toxin-induced apoptosis involving Fas, p53, Bcl-xL, Bcl-2, Bax and caspase-3 signaling pathways in human chondrocytes

    To investigate the effects of T-2 toxin on expressions of Fas, p53, Bcl-xL, Bcl-2, Bax and caspase-3 on human chondrocytes.

    **g-hong Chen, Jun-ling Cao, Yong-lie Chu in Journal of Zhejiang University SCIENCE B (2008)

  5. Article

    Proteomic analysis of HuH-7 cells harboring in vitro-transcribed full-length hepatitis C virus 1b RNA

    The present study examined the differential expression of proteins in HuH-7 cells and HuH-7 cells harboring in vitro-transcribed full-length hepatitis C virus 1b RNA (HuH-7-HCV), and elucidated the cellular respo...

    Meng Xun, Si-hai Zhao, Chun-xia Cao, Juan Song in Acta Pharmacologica Sinica (2008)