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Article
Probing the structural requirements for thyroid hormone receptor inhibitory activity of sulfonylnitrophenylthiazoles (SNPTs) using 2D-QSAR and 3D-QSAR approaches
A series of sulfonylnitrophenylthiazoles derivatives were identified as effective targeting agents that block the interaction of the thyroid hormone receptor with its coactivators. In this work, in order to an...
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Article
The intracellular mechanism of action on Escherichia coli of BF2-A/C, two analogues of the antimicrobial peptide Buforin 2
In the present study, the antimicrobial peptides BF2-A and BF2-C, two analogues of Buforin 2, were chemically synthesized and the activities were assayed. To elucidate the bactericidal mechanism of BF2-A/C and...
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Article
Inhibition of Fe-induced colon oxidative stress by lactobacilli in mice
Iron (Fe) can promote hydrogen peroxide (H2O2) and hydroxyl radical generation in the colonic surface and promote growth of Fe-dependent bacteria. Some Lactobacillus strains are resistant to oxygen free-radicals,...
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Chapter and Conference Paper
Research of Traffic Evacuation Methods of Unexpected Events
To rescue and evacuate people of unexpected events in city, it is very necessary to organize traffic system. On the base of analyzing traffic characteristics of unexpected events, traffic evacuation methods ar...
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Article
Oxidative stress induced by high-glucose diet in liver of C57BL/6J mice and its underlying mechanism
High glycemic index diet can induce multiple diseases. Many research indicated that oxidative stress played important role in many pathological conditions. However, the impact of gene expression and dietary ha...
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Article
The effect of diet with different glycemic index on the redox status of duodenums in mice and its underlying mechanism
The mechanisms of some gastrointestinal disease related to high-GI (glycemic index) diet are unknown. Oxidative stress is a well-recognized mechanism in many pathological conditions. Some study reported dietar...
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Article
Microarray analysis of high-glucose diet-induced changes in mRNA expression in jejunums of C57BL/6J mice reveals impairment in digestion, absorption
Long term intake of high-glucose diet (HGD) may induce many diseases such as dyslipidemia, fatty liver and diabetes disease. Most of the research for molecular mechanisms of the association between HGD and the...
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Article
Expression of Genes Associated with Bone Resorption is Increased and Bone Formation is Decreased in Mice Fed a High-Fat Diet
A high-fat diet (HFD) leads to an increased risk of osteoporosis-related fractures, but the molecular mechanisms for its effects on bone metabolism have rarely been addressed. The present study investigated th...
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Article
Antihypertensive effect of alcalase generated mung bean protein hydrolysates in spontaneously hypertensive rats
Mung bean protein isolates were hydrolyzed by alcalase and neutrase, respectively, and the angiotensin I-converting enzyme (ACE) inhibitory activities of the enzymatic hydrolysates were determined at different...
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Article
Cloning and functional characterization of two cDNAs encoding NADPH-dependent 3-ketoacyl-CoA reductased from develo** cotton fibers
Genes encoding enzymes involved in biosynthesis of very long chain fatty acids were significantly up-regulated during early cotton fiber development. Two cDNAs, GhKCR1 and GhKCR2 encoding putative cotton 3-ketoac...
