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Open AccessEffect of Pravastatin on Kidney Function in Patients with Dyslipidemia and Type 2 Diabetes Mellitus: A Multicenter Prospective Observational Study
Several studies have reported that pravastatin can mitigate the progression of kidney disease, but limited evidence exists regarding its effects on kidney function in Asian patients. This multicenter prospecti...
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Article
A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Article
Open AccessIn-depth correlation analysis between tear glucose and blood glucose using a wireless smart contact lens
Tears have emerged as a promising alternative to blood for diagnosing diabetes. Despite increasing attempts to measure tear glucose using smart contact lenses, the controversy surrounding the correlation betwe...
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Article
Open AccessClinical and radiological outcomes of non-window-type bioactive glass–ceramic cage in single-level ACDF versus PEEK cage filled with autologous bone
Bioactive glass–ceramic (BGC) cage is a substitute for polyether ether ketone (PEEK) cages in anterior cervical discectomy and fusion (ACDF). Only a few comparative studies exist using PEEK and non-window-type...
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Article
Open AccessTranscriptome and Micro-CT analysis unravels the cuticle modification in phosphine-resistant stored grain insect pest, Tribolium castaneum (Herbst)
Phosphine (PH3) resistance in stored grain insect pests poses a significant challenge to effective pest control strategies worldwide. This study delved into understanding PH3-resistant mechanism, with the objecti...
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Open AccessAuthor Correction: Mitochondria-derived peptide SHLP2 regulates energy homeostasis through the activation of hypothalamic neurons
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Open AccessComparisons of the prediction models for undiagnosed diabetes between machine learning versus traditional statistical methods
We compared the prediction performance of machine learning-based undiagnosed diabetes prediction models with that of traditional statistics-based prediction models. We used the 2014–2020 Korean National Health...
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Article
Open AccessMitochondria-derived peptide SHLP2 regulates energy homeostasis through the activation of hypothalamic neurons
Small humanin-like peptide 2 (SHLP2) is a mitochondrial-derived peptide implicated in several biological processes such as aging and oxidative stress. However, its functional role in the regulation of energy h...
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Open AccessAblation of the deubiquitinase USP15 ameliorates nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
Nonalcoholic fatty liver disease (NAFLD) occurs due to the accumulation of fat in the liver, leading to fatal liver diseases such as nonalcoholic steatohepatitis (NASH) and cirrhosis. Elucidation of the molecu...
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Open AccessGlobal spatial distribution of Chromolaena odorata habitat under climate change: random forest modeling of one of the 100 worst invasive alien species
Anthropogenic activities and global climate change increase the risk of Chromolaena odorata invasion and habitat expansion. To predict its global distribution and habitat suitability under climate change, a rando...
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Open AccessTcf7l2 in hepatocytes regulates de novo lipogenesis in diet-induced non-alcoholic fatty liver disease in mice
Non-alcoholic fatty liver disease (NAFLD) associated with type 2 diabetes may more easily progress towards severe forms of non-alcoholic steatohepatitis (NASH) and cirrhosis. Although the Wnt effector transcri...
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Article
Open AccessDetection of the 40 Hz auditory steady-state response with optically pumped magnetometers
Magnetoencephalography (MEG) is a functional neuroimaging technique that noninvasively detects the brain magnetic field from neuronal activations. Conventional MEG measures brain signals using superconducting ...
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Article
Open AccessDapagliflozin attenuates diabetes-induced diastolic dysfunction and cardiac fibrosis by regulating SGK1 signaling
Recent studies have reported improved diastolic function in patients administered sodium-glucose cotransporter 2 inhibitors (SGLT2i). We aimed to investigate the effect of dapagliflozin on left ventricular (LV...
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Open AccessThe effects of the voglibose on non-alcoholic fatty liver disease in mice model
The α-glucosidase inhibitor (α-GI) delays the intestinal absorption of glucose, which reduces postprandial hepatic glucose intake. This mechanism is considered to be effective in treating non-alcoholic fatty l...
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Article
Open AccessDifferences in complication patterns in subgroups of type 2 diabetes according to insulin resistance and beta-cell function
This study aimed to determine whether the patterns of diabetic complications differed when patients with type 2 diabetes mellitus (T2DM) were simply classified according to insulin sensitivity and beta-cell fu...
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Article
First report of powdery mildew caused by Podosphaera xanthii on Matricaria chamomilla in Korea
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Open AccessEzetimibe combination therapy with statin for non-alcoholic fatty liver disease: an open-label randomized controlled trial (ESSENTIAL study)
The effect of ezetimibe, Niemann-Pick C1-like 1 inhibitor, on liver fat is not clearly elucidated. Our primary objective was to evaluate the efficacy of ezetimibe plus rosuvastatin versus rosuvastatin monother...
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Article
Isolation and Discovery of Small Peptides as Potential Biomarkers in Three Rice Cultivars Using Surface-Enhanced Laser Desorption/Ionization (SELDI) Time-of-Flight (TOF) Mass Spectrometry (MS)
Low molecular weight proteins are promising molecules for rice plants. The objectives of this study were to develop an optimized method for protein extractions and protein chips and to perform practical applic...
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Open AccessReal-world evidence on the strategy of olmesartan-based triple single-pill combination in Korean hypertensive patients: a prospective, multicenter, observational study (RESOLVE-PRO)
In this prospective, multicenter, non-comparative observational study, the effectiveness and safety of the triple single-pill combination (SPC) of olmesartan/amlodipine/hydrochlorothiazide (OM/AML/HCTZ) were e...
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First report of powdery mildew caused by Podosphaera erigerontis-canadensis on Conyza sumatrensis in Korea
