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  1. Article

    Open Access

    Comprehensive renoprotective effects of ipragliflozin on early diabetic nephropathy in mice

    Clinical and experimental studies have shown that sodium glucose co-transporter 2 inhibitors (SGLT2i) contribute to the prevention of diabetic kidney disease progression. In order to clarify its pharmacologica...

    Michitsugu Kamezaki, Tetsuro Kusaba, Kazumi Komaki, Yohei Fushimura… in Scientific Reports (2018)

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  2. Article

    Open Access

    D-Glutamate is metabolized in the heart mitochondria

    D-Amino acids are enantiomers of L-amino acids and have recently been recognized as biomarkers and bioactive substances in mammals, including humans. In the present study, we investigated functions of the novel.....

    Makoto Ariyoshi, Masumi Katane, Kenji Hamase, Yurika Miyoshi… in Scientific Reports (2017)

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