-
Article
Open AccessAssociation of apolipoprotein E gene polymorphisms with blood lipids and their interaction with dietary factors
Several candidate genes have been identified in relation to lipid metabolism, and among these, lipoprotein lipase (LPL) and apolipoprotein E (APOE) gene polymorphisms are major sources of genetically determined v...
-
Article
Open AccessAssociations between APOE and low-density lipoprotein cholesterol genotypes and cognitive and physical capability: the HALCyon programme
The APOE ε2/3/4 genotype has been associated with low-density lipoprotein cholesterol (LDL-C) and Alzheimer disease. However, evidence for associations with measures of cognitive performance in adults without dem...
-
Article
Open AccessPhysical capability and subsequent positive mental wellbeing in older people: findings from five HALCyon cohorts
Objective measures of physical capability are being used in a growing number of studies as biomarkers of healthy ageing. However, very little research has been done to assess the impact of physical capability ...
-
Article
Open AccessEvaluation of seven common lipid associated loci in a large Indian sib pair study
Genome wide association studies (GWAS), mostly in Europeans have identified several common variants as associated with key lipid traits. Replication of these genetic effects in South Asian populations is impor...