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  1. Article

    Open Access

    Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells

    Rare multipotent stem cells replenish millions of blood cells per second through a time-consuming process, passing through multiple stages of increasingly lineage-restricted progenitors. Although insults to th...

    Joana Carrelha, Stefania Mazzi, Axel Winroth, Michael Hagemann-Jensen in Nature Immunology (2024)

  2. Article

    Open Access

    Platelet and myeloid lineage biases of transplanted single perinatal mouse hematopoietic stem cells

    Karin Belander Strålin, Joana Carrelha, Axel Winroth, Christoph Ziegenhain in Cell Research (2023)

  3. No Access

    Article

    Epigenetic programming defines haematopoietic stem cell fate restriction

    Haematopoietic stem cells (HSCs) are multipotent, but individual HSCs can show restricted lineage output in vivo. Currently, the molecular mechanisms and physiological role of HSC fate restriction remain unkno...

    Yiran Meng, Joana Carrelha, Roy Drissen, **ying Ren, Bowen Zhang in Nature Cell Biology (2023)

  4. Article

    Open Access

    Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

    Yolk sac (YS) hematopoiesis is critical for the survival of the embryo and a major source of tissue-resident macrophages that persist into adulthood. Yet, the transcriptional and epigenetic regulation of YS he...

    Wen Hao Neo, Yiran Meng, Alba Rodriguez-Meira in Nature Communications (2021)

  5. No Access

    Article

    Thermal Behavior of Quasi-isotropic Strand and Stacked-Tape Conductor

    In this study, the thermal processes of a quasi-isotropic conductor in response to a heat disturbance are studied in detail, by combining simulations and experiments. A simulation model considering the anisotr...

    Yueyin Wang, Yinshun Wang, Yang Nie in Journal of Superconductivity and Novel Mag… (2020)

  6. Article

    Open Access

    Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing

    Hematopoietic ageing involves declining erythropoiesis and lymphopoiesis, leading to frequent anaemia and decreased adaptive immunity. How intrinsic changes to the hematopoietic stem cells (HSCs), an altered m...

    Simona Valletta, Alexander Thomas, Yiran Meng, **ying Ren in Nature Communications (2020)

  7. Article

    Open Access

    Disrupted brain network dynamics and cognitive functions in methamphetamine use disorder: insights from EEG microstates

    Dysfunction in brain network dynamics has been found to correlate with many psychiatric disorders. However, there is limited research regarding resting electroencephalogram (EEG) brain network and its associat...

    Tianzhen Chen, Hang Su, Na Zhong, Haoye Tan, **aotong Li, Yiran Meng in BMC Psychiatry (2020)

  8. No Access

    Article

    Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells

    Analysis of transplantation of single haematopoietic stem cells in mice defines stable lineage-restricted fates in long-term self-renewing multipotent stem cells, including a class of multipotent stem cells th...

    Joana Carrelha, Yiran Meng, Laura M. Kettyle, Tiago C. Luis, Ruggiero Norfo in Nature (2018)

  9. No Access

    Article

    Air Atmospheric Dielectric Barrier Discharge Plasma Induced Germination and Growth Enhancement of Wheat Seed

    Air atmospheric dielectric barrier discharge plasma (DBD) was attempted to pretreat wheat seed to improve its germination and growth in this study. The effects of the DBD plasma treatment on the wheat seed ger...

    Yujuan Li, Tiecheng Wang, Yiran Meng in Plasma Chemistry and Plasma Processing (2017)

  10. No Access

    Article

    Enhancement of Germination and Seedling Growth of Wheat Seed Using Dielectric Barrier Discharge Plasma with Various Gas Sources

    The influences of non-thermal discharge plasma treatment on wheat seed germination and seedling growth were investigated using a dielectric barrier discharge (DBD) plasma system at atmospheric pressure and ro...

    Yiran Meng, Guangzhou Qu, Tiecheng Wang in Plasma Chemistry and Plasma Processing (2017)