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  1. No Access

    Article

    A new approach to modeling the cure rate in the presence of interval censored data

    We consider interval censored data with a cured subgroup that arises from longitudinal followup studies with a heterogeneous population where a certain proportion of subjects is not susceptible to the event of...

    Suvra Pal, Yingwei Peng, Wisdom Aselisewine in Computational Statistics (2024)

  2. No Access

    Article

    Improving marginal hazard ratio estimation using quadratic inference functions

    Clustered and multivariate failure time data are commonly encountered in biomedical studies and a marginal regression approach is often employed to identify the potential risk factors of a failure. We consider...

    Hongkai Liang, **aoguang Wang, Yingwei Peng, Yi Niu in Lifetime Data Analysis (2023)

  3. No Access

    Article

    Rejoinder on: Nonparametric estimation in mixture cure models with covariates

    Ana López-Cheda, Yingwei Peng, María Amalia Jácome in TEST (2023)

  4. No Access

    Article

    Nonparametric estimation in mixture cure models with covariates

    Nonparametric estimation methods for the cure rate and the distribution of the failure time of uncured subjects with covariates for censored survival data have attracted much attention in the last few years. T...

    Ana López-Cheda, Yingwei Peng, María Amalia Jácome in TEST (2023)

  5. No Access

    Chapter

    A Selective Overview of Statistical Methods for Identification of the Treatment-Sensitive Subsets of Patients

    Identification of a subset of patients who may benefit from or be sensitive to a specific type of treatment has become a very important research topic in clinical trials and other types of clinical research. S...

    **nyi Ge, Yingwei Peng, Dongsheng Tu in Advances and Innovations in Statistics and… (2022)

  6. No Access

    Article

    An additive hazards frailty model with semi-varying coefficients

    Proportional hazards frailty models have been extensively investigated and used to analyze clustered and recurrent failure times data. However, the proportional hazards assumption in the models may not always ...

    Zhongwen Zhang, **aoguang Wang, Yingwei Peng in Lifetime Data Analysis (2022)

  7. No Access

    Article

    Maximum likelihood estimation for length-biased and interval-censored data with a nonsusceptible fraction

    Left-truncated data are often encountered in epidemiological cohort studies, where individuals are recruited according to a certain cross-sectional sampling criterion. Length-biased data, a special case of lef...

    Pao-sheng Shen, Yingwei Peng, Hsin-Jen Chen, Chyong-Mei Chen in Lifetime Data Analysis (2022)

  8. No Access

    Article

    A support vector machine based semiparametric mixture cure model

    The mixture cure model is an extension of standard survival models to analyze survival data with a cured fraction. Many developments in recent years focus on the latency part of the model to allow more flexibl...

    Peizhi Li, Yingwei Peng, ** Jiang, Qingli Dong in Computational Statistics (2020)

  9. Article

    Open Access

    Region-specific glucocorticoid receptor promoter methylation has both positive and negative prognostic value in patients with estrogen receptor-positive breast cancer

    The glucocorticoid receptor (NR3C1, GR) is frequently downregulated in breast tumors, and evidence suggests it acts as a tumor suppressor in estrogen receptor-positive (ER+) breast cancer. We previously found tha...

    Hilary Snider, Brithica Villavarajan, Yingwei Peng in Clinical Epigenetics (2019)

  10. Article

    Open Access

    Imaging use for low back pain by Ontario primary care clinicians: protocol for a mixed methods study – the Back ON study

    At any one time, one in every five Canadians has low back pain (LBP), and LBP is one of the most common health problems in primary care. Guidelines recommend that imaging not be routinely performed in patients...

    Simon D. French, Michael E. Green, R. Sacha Bhatia in BMC Musculoskeletal Disorders (2019)

  11. No Access

    Article

    Jointly modeling longitudinal proportional data and survival times with an application to the quality of life data in a breast cancer trial

    Motivated by the joint analysis of longitudinal quality of life data and recurrence free survival times from a cancer clinical trial, we present in this paper two approaches to jointly model the longitudinal p...

    Hui Song, Yingwei Peng, Dongsheng Tu in Lifetime Data Analysis (2017)

  12. No Access

    Article

    Joint modeling of longitudinal proportional measurements and survival time with a cure fraction

    In cancer clinical trials and other medical studies, both longitudinal measurements and data on a time to an event (survival time) are often collected from the same patients. Joint analyses of these data would...

    Hui Song, YingWei Peng, DongSheng Tu in Science China Mathematics (2016)

  13. No Access

    Chapter

    Recent Development in the Joint Modeling of Longitudinal Quality of Life Measurements and Survival Data from Cancer Clinical Trials

    In cancer clinical trials, longitudinal Quality of Life (QoL) measurements and survival time on a patient may be analyzed by joint models, which provide more efficient estimation than modeling QoL data and sur...

    Hui Song, Yingwei Peng, Dongsheng Tu in Advanced Statistical Methods in Data Science (2016)

  14. No Access

    Article

    Integrating health-related quality of life findings from randomized clinical trials into practice: an international study of oncologists’ perspectives

    Although health-related quality of life (HRQL) is increasingly assessed in randomized controlled trials (RCTs), HRQL findings are not always incorporated into clinical decision making. We examined the current ...

    Julie Rouette, Jane Blazeby, Madeleine King, Melanie Calvert in Quality of Life Research (2015)

  15. No Access

    Article

    Semiparametric estimation methods for the accelerated failure time mixture cure model

    This paper provides an overview of two semiparametric estimation methods recently proposed in the literature for the accelerated failure time mixture cure model. We prove that the two estimation methods are as...

    Jiajia Zhang, Yingwei Peng in Journal of the Korean Statistical Society (2012)

  16. No Access

    Article

    An extended cure model and model selection

    We propose a novel interpretation for a recently proposed Box–Cox transformation cure model, which leads to a natural extension of the cure model. Based on the extended model, we consider an important issue of...

    Yingwei Peng, Jianfeng Xu in Lifetime Data Analysis (2012)

  17. No Access

    Article

    Accelerated hazards mixture cure model

    We propose a new cure model for survival data with a surviving or cure fraction. The new model is a mixture cure model where the covariate effects on the proportion of cure and the distribution of the failure ...

    Jiajia Zhang, Yingwei Peng in Lifetime Data Analysis (2009)

  18. No Access

    Article

    A marginal regression model for multivariate failure time data with a surviving fraction

    A marginal regression approach for correlated censored survival data has become a widely used statistical method. Examples of this approach in survival analysis include from the early work by Wei et al. (J Am ...

    Yingwei Peng, Jeremy M. G. Taylor, Binbing Yu in Lifetime Data Analysis (2007)

  19. Article

    Open Access

    Linkage analysis of systolic blood pressure: a score statistic and computer implementation

    A genome-wide linkage analysis was conducted on systolic blood pressure using a score statistic. The randomly selected Replicate 34 of the simulated data was used. The score statistic was applied to the sibshi...

    Kai Wang, Yingwei Peng in BMC Genetics (2003)