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  1. Article

    Open Access

    Novel nomograms based on microvascular invasion grade for early-stage hepatocellular carcinoma after curative hepatectomy

    Microvascular invasion (MVI) is a critical risk factor for postoperative recurrence of hepatocellular carcinoma (HCC). This study aimed to firstly develop and validate nomograms based on MVI grade for predicti...

    Hengkai Chen, Honghao Ye, Linfang Ye, Fangzhou Lin, Yingjun Shi in Scientific Reports (2024)

  2. Article

    Open Access

    LncRNA HOTTIP as a diagnostic biomarker for acute respiratory distress syndrome in patients with sepsis and to predict the short-term clinical outcome: a case-control study

    The present research aims to investigate the clinical diagnostic value of LncRNA HOXA distal transcript antisense RNA (HOTTIP) in acute respiratory distress syndrome (ARDS) of sepsis and its predictive signifi...

    Weitao Shi, Wang Zhu, Jiani Yu, Yingjun Shi, Yuliang Zhao in BMC Anesthesiology (2024)

  3. Article

    Open Access

    HIF-1α and HDAC1 mediated regulation of FAM99A-miR92a signaling contributes to hypoxia induced HCC metastasis

    Bixing Zhao, Kun Ke, Yingchao Wang, Fei Wang in Signal Transduction and Targeted Therapy (2020)

  4. Article

    Open Access

    Antioxidant preconditioning improves therapeutic outcomes of adipose tissue-derived mesenchymal stem cells through enhancing intrahepatic engraftment efficiency in a mouse liver fibrosis model

    Although it has been preclinically suggested that adipose tissue-derived mesenchymal stem cell (ADSC)-based therapy could effectively treat chronic liver diseases, the hepatic engraftment of ADSCs is still ext...

    Naishun Liao, Yingjun Shi, Yingchao Wang, Fangyu Liao in Stem Cell Research & Therapy (2020)

  5. Article

    Open Access

    Antioxidants inhibit cell senescence and preserve stemness of adipose tissue-derived stem cells by reducing ROS generation during long-term in vitro expansion

    Adipose tissue-derived mesenchymal stem cells (ADSCs) are promising candidates for regenerative medicine. However, long-term in vitro passaging leads to stemness loss and cell senescence of ADSCs, resulting in...

    Naishun Liao, Yingjun Shi, Cuilin Zhang, Youshi Zheng in Stem Cell Research & Therapy (2019)