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Article
Open AccessApplication of a next-generation sequencing (NGS) panel in newborn screening efficiently identifies inborn disorders of neonates
Newborn screening (NBS) has been implemented for neonatal inborn disorders using various technology platforms, but false-positive and false-negative results are still common. In addition, target diseases of NB...
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Article
Enhanced thermostability and antioxidant activity of Nattokinase by biogenic enrichment of selenium
Nattokinase was produced and enriched with selenium by liquid fermentation in a flask culture. Different concentrations of Na2SeO3 (0, 1, 5, 15, 30, 60 and 120 mg/L) were analysed for optimization purpose. Result...
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Article
Genome shuffling improved acid-tolerance and succinic acid production of Actinobacillus succinogenes
Succinic acid is widely applied to chemical, pharmaceutical, food, and agricultural industries. With the rapid development of these industries, a great demand of succinic acid is required. The acid-tolerance a...
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Article
Open AccessEpitope-loaded nanoemulsion delivery system with ability of extending antigen release elicits potent Th1 response for intranasal vaccine against Helicobacter pylori
Helicobacter pylori (H. pylori) infection remains a global public health issue, especially in Asia. Due to the emergence of antibiotic-resistant strains and the complexity of H. pylori infection, conventional vac...
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Article
Open AccessMultilayer Graphene with Chemical Modification as Transparent Conducting Electrodes in Organic Light-Emitting Diode
Graphene is a promising candidate for the replacement of the typical transparent electrode indium tin oxide in optoelectronic devices. Currently, the application of polycrystalline graphene films grown by chem...
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Article
Open AccessSilver Nanowires Modified with PEDOT: PSS and Graphene for Organic Light-Emitting Diodes Anode
Silver nanowires (AgNWs) networks are promising candidates for the replacement of indium tin oxide (ITO). However, the surface roughness of the AgNWs network is still too high for its application in optoelectr...
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Article
A new class of weights adapted to rough singular integrals and Marcinkiewicz integrals
In this paper, we introduce a new class of weights \( \bar A_p (\mathbb{R}^n ) \) which retains many fine properties ...
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Article
An implicit symmetry constraint of the modified Korteweg-de Vries (mKdV) equation
In this paper, an implicit symmetry constraint is calculated and its associated binary nonlinearization of the Lax pairs and the adjoint Lax pairs is carried out for the modified Korteweg-de Vries (mKdV) equat...
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Article
Projectively flat exponential Finsler metric
In this paper, we study a class of Finsler metric in the form F=αexp(β/α)+εβ, where α is a Riemannian metric and β is a 1-form, ε is a constant. We call F exponential Finsler metric. We proved that exponential Fi...
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Article
Construction and expression of retroviruses encoding dual drug resistance genes in human umbilical cord blood CD34+ cells
A series of retro viral vectors encoding humanmdr1 gene alone as wetl as in combination with either humanmgmt gene or human mutantSer 31-dhfr gene are engineered. The resultant retroviruses are us...