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Article
Open AccessSHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis
Stimulator of interferon genes (STING) activation induces type I interferons and pro-inflammatory cytokines which stimulate tumor antigen cross presentation and the adaptive immune responses against tumor. The...
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Article
Open AccessDiscovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis
Clinical success of IL-17/IL-23 pathway biologics for the treatment of moderate to severe psoriasis suggests that targeting RORγt, a master regulator for the proliferation and function of Th17 cells, could be ...
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Chapter and Conference Paper
Study on Optimal Path Changing Tools in CNC Turret Ty** Machine Based on Genetic Algorithm
This paper is aimed to find the optimum path of CNC turret ty** system to reduce the changing tools times and optimize tool movement routes to make up for the deficiency of CNC Turret Ty** machine producti...
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Chapter and Conference Paper
Study on Intelligent Multi-concentrates Feeding System for Dairy Cow
To implement precision feeding for dairy cow, an intelligent multi-concentrates feeding system was developed. The system consists of two parts, one is precision ingredients control subsystem, the other is mult...
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Article
Structure of N,N′,N″-tris(carboxymethyl)-1,3,5-benzenetricarboxamide trihydrate
The title compound, C15H15N3O9 · 3H2O, crystallizes in the centrosymmetric space group R \(\bar 3\) with a = 13.642...