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Article
Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer
Among the greatest hurdles in clinical management of prostate cancer (PCa) are the progression to lethal castration-resistant prostate cancer (CRPC) and the lack of suitable targeted therapies for advanced dis...
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Article
Open AccessGeomicrobial functional groups: A window on the interaction between life and environments
Microbes are well-known for their great diversity and abundance in modern natural environments. They also are believed to provide critical links among higher organisms and their associated environments. Howeve...
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Article
Late Devonian red tide and mass extinction
Molecular stratigraphical, carbonate carbon isotopic, stratigraphical and paleontological data show that algal booming, eutrophication, anoxia, hypersalinity, positive δ13C excursion and biomass decreasing occurr...
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Article
Topologic configuration of a graphoglyptid and its functional morphologic analysis
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Topologic analysis of representative Devonian graphoglyptids of China shows that a huge graphoglyptid clan ca...
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