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    Article

    Auto-regulatory RNA editing fine-tunes mRNA re-coding and complex behaviour in Drosophila

    Auto-regulatory feedback loops are a common molecular strategy used to optimize protein function. In Drosophila, many messenger RNAs involved in neuro-transmission are re-coded at the RNA level by the RNA-editing...

    Yiannis A. Savva, James E.C Jepson, Asli Sahin, Arthur U. Sugden in Nature Communications (2012)

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    Article

    RNA editing regulates transposon-mediated heterochromatic gene silencing

    Heterochromatin formation drives epigenetic mechanisms associated with silenced gene expression. Repressive heterochromatin is established through the RNA interference pathway, triggered by double-stranded RNA...

    Yiannis A. Savva, James E. C. Jepson, Yao-Jen Chang in Nature Communications (2013)

  3. Article

    Open Access

    Circuit analysis reveals a neural pathway for light avoidance in Drosophila larvae

    Understanding how neural circuits underlie behaviour is challenging even in the connectome era because it requires a combination of anatomical and functional analyses. This is exemplified in the circuit underl...

    Altar Sorkaç, Yiannis A. Savva, Doruk Savaş, Mustafa Talay in Nature Communications (2022)