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Open AccessMining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients
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Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins
The ongoing outbreak of viral pneumonia in China and across the world is associated with a new coronavirus, SARS-CoV-21. This outbreak has been tentatively associated with a seafood market in Wuhan, China, where ...
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Open AccessIdentification of tick-borne pathogen diversity by metagenomic analysis in Haemaphysalis longicornis from **nyang, China
A wide variety of pathogens could be maintained and transmitted by Haemaphysalis longicornis. The aim of this study is to systematically examine the variety of pathogens carried by Haemaphysalis longicornis, an i...
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Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin
Cross-species transmission of viruses from wildlife animal reservoirs poses a marked threat to human and animal health 1 . Bats have been recognized as one of the most important reservoirs for emerging v...
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Open AccessIntranasal infection and contact transmission of Zika virus in guinea pigs
Zika virus (ZIKV) is primarily transmitted to humans through mosquito bites or sexual contact. The excretion and persistence of contagious ZIKV in various body fluids have been well documented in ZIKV patients...
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Intra-host dynamics of Ebola virus during 2014
Since 2013, West Africa has encountered the largest Ebola virus (EBOV) disease outbreak on record, and Sierra Leone is the worst-affected country, with nearly half of the infections. By means of next-generatio...
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Erratum: Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone
Nature 524, 93–96 (2015); doi:10.1038/nature14490 This Letter should have contained an associated Creative Commons statement in the Author Information section. In addition, the Fig. 3c legend should have state...
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Open AccessIdentification of Bufavirus-1 and Bufavirus-3 in Feces of Patients with Acute Diarrhea, China
Bufavirus (BuV) is a newly discovered human parvovirus that has been detected in some countries. The current study was designed to understand the epidemic of BuV in China. Totally 1877 fecal specimens were col...
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Open AccessGenetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone
The genome sequences of 175 Ebola virus from five districts in Sierra Leone, collected during September–November 2014, show that the rate of virus evolution seems to be similar to that observed during previous...
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Trap** tobacco specific N-nitrosamines in Chinese-Virginia type tobacco extracting solution by porous material
Liquid adsorption of tobacco specific nitrosamines (TSNA) in the tobacco extracting solution by porous materials is reported, with the monitoring of standard LC–MS/MS technique, in order to reduce the environm...
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Close relationship between the 2009 H1N1 virus and South Dakota AIV strains
Although previous publications suggest the 2009 pandemic influenza A (H1N1) virus was reassorted from swine viruses of North America and Eurasia, the immediate ancestry still remains elusive due to the big evo...
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An easy-to-use site-directed mutagenesis method with a designed restriction site for convenient and reliable mutant screening
Site-directed mutagenesis (SDM) has been a very important method to probe the function-structure relationship of proteins. In this study, we introduced an easy-to-use, polymerase chain reaction (PCR)-based SDM...