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  1. Article

    Open Access

    GnRH-driven FTO-mediated RNA m6A modification promotes gonadotropin synthesis and secretion

    Gonadotropin precisely controls mammalian reproductive activities. Systematic analysis of the mechanisms by which epigenetic modifications regulate the synthesis and secretion of gonadotropin can be useful for...

    Hao-Qi Wang, Yi-Ran Ma, Yu-**n Zhang, Fan-Hao Wei, Yi Zheng, Zhong-Hao Ji in BMC Biology (2024)

  2. No Access

    Article

    Genome constitution and evolution of Elymus atratus (Poaceae: Triticeae) inferred from cytogenetic and phylogenetic analysis

    Elymus atratus (Nevski) Hand.-Mazz. is perennial hexaploid wheatgrass. It was assigned to the genus Elymus L. sensu stricto based on morphological characters. Its genome constitution has not been disentangled yet...

    Lu Tan, Dan-Dan Wu, Chang-Bing Zhang, Yi-Ran Cheng, Li-Na Sha, **ng Fan in Genes & Genomics (2024)

  3. No Access

    Article

    The roles of ETS transcription factors in liver fibrosis

    E26 transformation specific or E twenty-six (ETS) protein family consists of 28 transcription factors, five of which, named ETS1/2, PU.1, ERG and EHF, are known to involve in the development of liver fibrosis,...

    Li-Ye Zhang, Yong Tan, **ao-Jie Luo, Jiang-Feng Wu, Yi-Ran Ni in Human Cell (2023)

  4. No Access

    Article

    Ectopic expression of MmCYP1A1, a mouse cytochrome P450 gene, positively regulates stress tolerance in apple calli and Arabidopsis

    Ectopic expression of MmCYP1A1 gene from Mus musculus in apple calli and Arabidopsis increased the levels of melatonin and 6-hydroxymelatonin, and improved their stress resistance.

    **ao-Na Wang, Fei Yang, Jiu-Cheng Zhang, Yi-Ran Ren, Jian-** An in Plant Cell Reports (2023)

  5. Article

    Open Access

    The roles of long noncoding RNAs in the regulation of OCT4 expression

    OCT4 is a major transcription factor that maintains the pluripotency of stem cells, including embryonic stem cells, induced pluripotent stem cells and cancer stem cells. An increasing number of long noncoding ...

    Rui-Ting Zhou, Yi-Ran Ni, Fan-Jun Zeng in Stem Cell Research & Therapy (2022)

  6. Article

    Open Access

    Biosystematics studies on Elymus breviaristatus and Elymus sinosubmuticus (Poaceae: Triticeae)

    Elymus breviaristatus and Elymus sinosubmuticus are perennial herbs, not only morphologically similar but also sympatric distribution. The genome composition of E. sinosubmuticus has not been reported, and the re...

    Lu Tan, Qing-**ang Huang, Yang Song, Dan-Dan Wu, Yi-Ran Cheng in BMC Plant Biology (2022)

  7. Article

    Open Access

    Relationship between the structure and function of the transcriptional regulator E2A

    E proteins are transcriptional regulators that regulate many developmental processes in animals and lymphocytosis and leukemia in Homo sapiens. In particular, E2A, a member of the E protein family, plays a major ...

    Jia-Jie Liang, Hu Peng, Jiao-Jiao Wang in Journal of Biological Research-Thessaloniki (2021)

  8. No Access

    Article

    Apple MdSAT1 encodes a bHLHm1 transcription factor involved in salinity and drought responses

    This study identified a new bHLHm1 transcription factor MdSAT1 which functioned in mediating tolerance to salt and drought resistance.

    Yu-Ying Yang, Peng-Fei Zheng, Yi-Ran Ren, Yu-**n Yao, Chun-**ang You in Planta (2021)

  9. Article

    Open Access

    mTOR may interact with PARP-1 to regulate visible light-induced parthanatos in photoreceptors

    Excessive light exposure is a detrimental environmental factor that plays a critical role in the pathogenesis of retinal degeneration. However, the mechanism of light-induced death of retina/photoreceptor cell...

    Yi-Ran Pan, **g-Yao Song, Bin Fan, Ying Wang, Lin Che in Cell Communication and Signaling (2020)

  10. Article

    Open Access

    LINC00665 promotes breast cancer progression through regulation of the miR-379-5p/LIN28B axis

    Breast cancer is the most common malignant tumor among women worldwide. Although increasing evidence indicates that long noncoding RNAs (lncRNAs) play critical roles during breast tumorigenesis and progression...

    Wei Ji, Yu-Ling Diao, Yi-Ran Qiu, Jie Ge, Xu-Chen Cao, Yue Yu in Cell Death & Disease (2020)

  11. No Access

    Article

    Cloning and functional identification of a strigolactone receptor gene MdD14 in apple

    Strigolactones (SLs) are phytohomones that regulate shoot branching and hypocotyl elongation. Here, the strigolactone receptor gene MdD14 in apple was cloned. MdD14 was localized to the nucleus and cytoplasm. GUS...

    Yu-Ying Yang, Yi-Ran Ren, Peng-Fei Zheng in Plant Cell, Tissue and Organ Culture (PCTO… (2020)

  12. No Access

    Article

    Recovery of unstable digestion of vegetable waste by adding trace elements using the bicarbonate alkalinity to total alkalinity ratio as an early warning indicator

    Vegetable waste (VW) is highly perishable and susceptible to acidification during anaerobic digestion, which inhibits biogas production. Effective process monitoring, diagnosis and control are necessary to mai...

    Dong Li, Juan Sun, Qin Cao, Yichao Chen, **aofeng Liu, Yi Ran in Biodegradation (2019)

  13. No Access

    Article

    Genetic map** and salt tolerance of a novel D1-allelic mutant of rice (Oryza sativa L.)

    Plant height and grain shape are important traits that may affect yield in rice, and they therefore have enormous importance in breeding. A dwarf small-grain mutant (S525) was identified among progeny of the Indi...

    Wei-jiang Tian, **ao-qiong Zhang, **ao-wen Wang, Jia **e in Acta Physiologiae Plantarum (2018)

  14. No Access

    Article

    Apple MdMYC2 reduces aluminum stress tolerance by directly regulating MdERF3 gene

    Jasmonate (JA) and ethylene are involved in the regulation of the aluminum (Al)-induced growth inhibition. Although it has been reported that JA enhances Al-induced root-growth inhibition, its role in the regu...

    Jian-** An, **ao-Na Wang, Ji-Fang Yao, Yi-Ran Ren, Chun-**ang You in Plant and Soil (2017)

  15. Article

    Open Access

    SP1 and UTE1 Decoy ODNs inhibit activation and proliferation of hepatic stellate cells by targeting tissue inhibitors of metalloproteinase 1

    The excessive accumulation of extracellular matrix of hepatic fibrosis is positively correlated with tissue inhibitors of metalloproteinase 1 (TIMP1). Here we aimed to investigate whether TIMP1 may be down-reg...

    Dong Jia, Yi-Ran Ni, Yan-Qiong Zhang, Chun Rao, Jun Hou, He-Qing Tang in Cell & Bioscience (2016)

  16. No Access

    Article

    Adaptation to Nicotine Feeding in Myzus persicae

    Lineages of the generalist hemipteran herbivore Myzus persicae (green peach aphid) that have expanded their host range to include tobacco often have elevated nicotine tolerance. The tobacco-adapted M. persicae li...

    John S. Ramsey, Dezi A. Elzinga, Pooja Sarkar, Yi-Ran **n in Journal of Chemical Ecology (2014)

  17. No Access

    Article

    Enhanced viability of Lactobacillus reuteri for probiotics production in mixed solid-state fermentation in the presence of Bacillus subtilis

    In order to develop a multi-microbe probiotic preparation of Lactobacillus reuteri G8-5 and Bacillus subtilis MA139 in solid-state fermentation, a series of parameters were optimized sequentially in shake flask c...

    Yi-Ran Zhang, Hai-Rong **ong, **ao-Hua Guo in Folia Microbiologica (2014)

  18. No Access

    Article

    Role of DNA in Bacterial Aggregation

    The role of DNA in bacterial aggregation was determined using various types of DNA and Escherichia coli, a good model for investigating the correlation between added polymer and bacterial aggregation and adsorpti...

    Hui-Hui Liu, Yi-Ran Yang, **n-Cheng Shen, Zhi-Ling Zhang, ** Shen in Current Microbiology (2008)