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Open AccessLong COVID symptoms after 8-month recovery: persistent static lung hyperinflation associated with small airway dysfunction
Limited research has investigated the relationship between small airway dysfunction (SAD) and static lung hyperinflation (SLH) in patients with post-acute sequelae of COVID-19 (PASC) especially dyspnea and fat...
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Article
Open AccessBlood tryptase and thymic stromal lymphopoietin levels predict the risk of exacerbation in severe asthma
Some patients with severe asthma experience exacerbations despite receiving multiple therapy. The risk of exacerbation and heterogeneous response to treatment may be associated with specific inflammatory molec...
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Article
Open AccessFunctional parameters of small airways can guide bronchodilator use in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) may present comorbid obstructive lung diseases with small airway dysfunction (SAD). Existing guidelines suggest that inhaled bronchodilators should be used if the ratio of f...
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Article
Open AccessAn accurate prediction model to identify undiagnosed at-risk patients with COPD: a cross-sectional case-finding study
Underuse or unavailability of spirometry is one of the most important factors causing underdiagnosis of COPD. We reported the development of a COPD prediction model to identify at-risk, undiagnosed COPD patien...
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Article
Open AccessMeasuring (1,3)-β-D-glucan in tracheal aspirate, bronchoalveolar lavage fluid, and serum for detection of suspected Candida pneumonia in immunocompromised and critically ill patients: a prospective observational study
While Candida pneumonia is life-threatening, biomarker measurements to early detect suspected Candida pneumonia are lacking. This study compared the diagnostic values of measuring levels of (1, 3)-β-D-glucan in e...
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Article
Kinect-based Taiwanese sign-language recognition system
Gesture-recognition is an important component for many intelligent human–computer interaction applications. For example, a realtime sign-language recognition system would detect and interpret hand gestures. Ma...
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Article
Exhaled Nitric Oxide Predicts Eosinophilic Airway Inflammation in COPD
Chronic obstructive pulmonary disease (COPD) with eosinophilic airway inflammation may represent a unique phenotype, possibly with shared features of COPD and asthma. The role of exhaled nitric oxide (eNO) in ...
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Article
The Suppression Effects of Thalidomide on Human Lung Fibroblasts: Cell Proliferation, Vascular Endothelial Growth Factor Release, and Collagen Production
Expression of transforming growth factor (TGF)-β1 and increases in angiogenesis and deposition of extracellular matrix are the key features of tracheal granulation formation. The aim of this study was to investig...