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Article
Open AccessThe impact of the duration of the integrated disease management program on COPD-related outcomes
The aim of this study is to assess the impact of the duration of the integrated disease management (IDM) program on COPD-related outcomes in real-world setting.
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Article
Open AccessBlood monocyte levels predict the risk of acute exacerbations of chronic obstructive pulmonary disease: a retrospective case–control study
Monocytes were critical cells in the innate immune system. Monocyte recruitment to the lungs is a crucial process of pathophysiology in chronic obstructive pulmonary disease (COPD). Current evidence on the ass...
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Article
Open AccessBlood tryptase and thymic stromal lymphopoietin levels predict the risk of exacerbation in severe asthma
Some patients with severe asthma experience exacerbations despite receiving multiple therapy. The risk of exacerbation and heterogeneous response to treatment may be associated with specific inflammatory molec...
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Article
Open AccessTiotropium/Olodaterol treatment reduces cigarette smoke extract-induced cell death in BEAS-2B bronchial epithelial cells
Cigarette smoking is a critical risk factor for the destruction of lung parenchyma or the development of emphysema, which is characteristic of COPD. Disruption of epithelial layer integrity may contribute to l...
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Article
The comparison between adenocarcinoma and squamous cell carcinoma in lung cancer patients
There are several studies comparing the difference between adenocarcinoma (AC) and squamous cell carcinoma (SqCC) of lung cancer. However, seldom studies compare the different overall survival (OS) between AC ...
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Article
Synergistic Anticancer Effect of a Combination of Paclitaxel and 5-Demethylnobiletin Against Lung Cancer Cell Line In Vitro and In Vivo
Lung cancer remains a highly prevalent disease and a leading cause of cancer-related deaths worldwide. Currently, exploring antitumor drugs derived from herbs used in traditional Chinese medicine is increasing...
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Article
Chidamide alleviates TGF-β-induced epithelial–mesenchymal transition in lung cancer cell lines
Transforming growth factor-β (TGF-β)-induced epithelial–mesenchymal transition is a critical process in the initiation of metastasis of various types of cancer. Chidamide is a class I histone deacetylase inhib...
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Article
E-forms in e-business
The form-based application framework is proposed as a straight solution for E-business applications. A Rapid Application Development (RAD) tool FormNet is designed for develo** complex enterprise network app...