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  1. Article

    Open Access

    Activation of Nrf2 by the dengue virus causes an increase in CLEC5A, which enhances TNF-α production by mononuclear phagocytes

    Infection by the dengue virus (DENV) threatens global public health due to its high prevalence and the lack of effective treatments. Host factors may contribute to the pathogenesis of DENV; herein, we investig...

    Yi-Lin Cheng, Yee-Shin Lin, Chia-Ling Chen, Tsung-Ting Tsai in Scientific Reports (2016)

  2. Article

    Open Access

    Lichen elemental composition distinguishes anthropogenic emissions from dust storm inputs and differs among species: Evidence from **linhot, Inner Mongolia, China

    To test the applicability of lichens in the biomonitoring of atmospheric elemental deposition in a typical steppe zone of Inner Mongolia, China, six foliose lichens (Physcia aipolia, PA; P. tribacia, PT; Xanthori...

    Hua-Jie Liu, Shi-Bo Fang, Si-Wa Liu, Liang-Cheng Zhao, **u-** Guo in Scientific Reports (2016)

  3. Article

    Open Access

    Characterization of transcriptional modules related to fibrosing-NAFLD progression

    Based on the severity of liver fibrosis, low or high-risk profile of develo** end-stage liver disease was present in nonalcoholic fatty liver disease (NAFLD). However, the mechanisms inducing transition from...

    Yi Lou, Guo-Yan Tian, Yu Song, Yin-Lan Liu, Yi-Dan Chen, Jun-** Shi in Scientific Reports (2017)

  4. Article

    Open Access

    Immunization with alkyl hydroperoxide reductase subunit C reduces Fusobacterium nucleatum load in the intestinal tract

    Fusobacterium nucleatum (Fn) is an important tumour-associated bacterium in colorectal cancer (CRC). The antioxidant protein alkyl hydroperoxide reductase subunit C (AhpC) can induce stro...

    Song-He Guo, Hai-Fang Wang, Zhi-Gang Nian, Yi-Dan Wang, Qiu-Yao Zeng in Scientific Reports (2017)

  5. Article

    Open Access

    MRE11-RAD50-NBS1 promotes Fanconi Anemia R-loop suppression at transcription–replication conflicts

    Ectopic R-loop accumulation causes DNA replication stress and genome instability. To avoid these outcomes, cells possess a range of anti-R-loop mechanisms, including RNaseH that degrades the RNA moiety in R-lo...

    Emily Yun-Chia Chang, Shuhe Tsai, Maria J. Aristizabal in Nature Communications (2019)

  6. Article

    Open Access

    Cognitive impairment and associated risk factors in older adult hemodialysis patients: a cross-sectional survey

    The clinical epidemiological features of cognitive impairment in Chinese older adult patients undergoing hemodialysis are not clear, we aimed to identify the extent and patterns of cognitive impairment among t...

    Yang Luo, Anne M. Murray, Yi-Dan Guo, Ru Tian, Peng-Peng Ye, **n Li in Scientific Reports (2020)

  7. Article

    Open Access

    Microbiome diversity of cotton aphids (Aphis gossypii) is associated with host alternation

    Aphids are infected by a series of bacteria that can help them survive on specific host plants. However, the associations between aphids and these bacteria are not clear, and the bacterial communities in many ...

    Yan-jie Ma, Hao-peng He, Hai-meng Zhao, Yi-dan **an, Hui Guo in Scientific Reports (2021)

  8. Article

    Open Access

    Organophotocatalysed synthesis of 2-piperidinones in one step via [1 + 2 + 3] strategy

    Six-membered N-containing heterocycles, such as 2-piperidinone derivatives, with diverse substitution patterns are widespread in natural products, drug molecules and serve as key precursors for piperidines. Thus,...

    Yi-Dan Du, Shan Wang, Hai-Wu Du, **ao-Yong Chang, **ao-Yi Chen in Nature Communications (2023)