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Article
Extracting Rock Parameters Through Digital Drilling Test
Rapid and partial acquisition are features of rock drilling for obtaining rock properties. Most previous research has primarily concentrated on how to quickly obtain rock mechanics parameters, with limited emp...
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Article
In situ synthesis of three-dimensional electrospun polyacrylonitrile nanofiber network reinforced silica aerogel for high-efficiency oil/water separation
In situ electrospun 3D polyacrylonitrile (PAN) nanofiber-reinforced (EPNR) silica aerogel monoliths were prepared through methyltriethoxysilane–trimethylchlorosilane modification followed by ambient pressure d...
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Article
Lighting up kinase contacts in situ
A second-timescale optogenetic strategy DeKinomics was developed, enabling the study of downstream events of kinases in a gain-of-function manner. Using this technique, UBA1, an E1 enzyme that initiates the ub...
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Article
Open AccessTargeting the up-regulated CNOT3 reverses therapeutic resistance and metastatic progression of EGFR-mutant non-small cell lung cancer
Lung cancer is the leading cause of cancer-related mortality worldwide. CNOT3, a subunit of the CCR4-NOT complex, has recently been suggested to be overexpressed in lung cancer and involved in tumor malignancy...
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Article
Open AccessDesigning pentapartitioned neutrosophic cubic set aggregation operator-based air pollution decision-making model
Environmental pollution is a global concern that has economic and health implications. Therefore, proper estimation using precise modeling can help in decision-making to address this externality. In science an...
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Article
Open AccessCorrelations between geomagnetic field and global occurrence of cardiovascular diseases: evidence from 204 territories in different latitude
The correlation between stable geomagnetic fields and unstable geomagnetic activities with mortality, incidence, and prevalence of cardiovascular diseases (CVDs) remains ambiguous.
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Article
Chiral Polymer-Mediated Pd@MOF-808 for Efficient Sequential Asymmetric Reaction
The design and construction of organocatalysts that combined the homogeneous and heterogeneous natures to realize efficient catalysis are highly desired and challenging. Functionalized-polymers, a kind of flex...
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Article
AuPd Alloys and Chiral Proline Dual-Functionalized NH2-UiO-66 Catalysts for Tandem Oxidation/Asymmetric Aldol Reactions
Rational design and precise engineering of a multifunctional catalyst at the molecular level to fulfill a multi-step tandem procedure still face serious challenges. Here, we first constructed two metal alloy N...
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Article
Open AccessTreating traumatic brain injury at sea: how to improve the skills and capabilities of the naval medical personnel
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Article
Open AccessPhenylalanine impairs insulin signaling and inhibits glucose uptake through modification of IRβ
Whether amino acids act on cellular insulin signaling remains unclear, given that increased circulating amino acid levels are associated with the onset of type 2 diabetes (T2D). Here, we report that phenylalan...
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Article
Open AccessPiezo1 promoted hepatocellular carcinoma progression and EMT through activating TGF-β signaling by recruiting Rab5c
Piezo1 has been revealed to play a regulatory role in vascular development and progression of variety tumors. However, whether and how the progression of hepatocellular carcinoma (HCC) regulated by Piezo1 rema...
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Article
Evolution of microstructure in reheated coarse-grained zone of G115 novel martensitic heat-resistant steel
Based on the thermal simulation method, a systematical analysis was conducted on the effect of welding peak temperature and the cooling time that takes place from 800 to 500 °C on microstructure, precipitates,...
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Article
Effect of Ce on solute redistribution in liquid ahead of solid–liquid interface during solidification of Fe–4 wt.%Si alloy
The high efficiency of Ce addition in grain refinement of δ-ferrite in a cast Fe–4 wt.%Si alloy was verified. In order to further understand the solute effect of Ce on the grain refinement of δ-ferrite, the co...
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Article
Open AccessProgrammed cell death 10 promotes metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma via PP2Ac-mediated YAP activation
Tumour metastasis is the main cause of postoperative tumour recurrence and mortality in patients with hepatocellular carcinoma (HCC), but the underlying mechanism remains unclear. Accumulating evidence has dem...
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Article
Variation of computed tomographic angiography–based fractional flow reserve after transcatheter aortic valve implantation
We sought to identify the impact of transcatheter aortic valve implantation (TAVI) on changes of fractional flow reserve computed tomography (FFRCT) values and the associated clinical impact.
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Article
Open AccessThe RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation
RNA-binding proteins (RBPs) function as master regulators of gene expression. Alterations in RBP expression and function are often observed in cancer and influence critical pathways implicated in tumor initiat...
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Article
Open AccessEfficacy and Safety of Dulaglutide Monotherapy Compared to Glimepiride in Oral Antihyperglycemic Medication-Naïve Chinese patients with Type 2 Diabetes: A Post Hoc Analysis of AWARD-CHN1
Glucagon-like peptide (GLP)-1 receptor agonists are glucose-lowering agents associated with weight loss, cardiovascular benefits, and low hypoglycemic risk and are recommended by recent guidelines as first-lin...
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Article
Open AccessA LASSO-derived risk model for long-term mortality in Chinese patients with acute coronary syndrome
The formal risk assessment is essential in the management of acute coronary syndrome (ACS). In this study, we develop a risk model for the prediction of 3-year mortality for Chinese ACS patients with machine l...
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Article
An accounting of the external environmental costs of coal in Inner Mongolia using the pollution damage method
Although coal makes substantial contributions to economic development, it also causes negative impacts on the ecological environment. To assess the real costs associated with the environmental degradation caus...
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Chapter and Conference Paper
Research on Early Kick Detection with Signal Distortion of Ultrasonic Doppler
A non-contact ultrasonic Doppler system, whose signal distortion can reveal the distribution of gas in wellbore when gas kick occurs, is presented for monitoring the status of drilling fluid in downhole to red...
