5 Result(s)

Article

Histone H3 Mutations in Cancer

Histone modifications are one form of epigenetic information that relate closely to gene regulation. Aberrant histone methylation caused by alteration in chromatin-modifying enzymes has long been implicated in...

Yi Ching Esther Wan, Jiaxian Liu, Kui Ming Chan in Current Pharmacology Reports (2018)

Article

Cancer-associated histone mutation H2BG53D disrupts DNA–histone octamer interaction and promotes oncogenic phenotypes

Yi Ching Esther Wan, Tsz Chui Sophia Leung… in Signal Transduction and Targeted Therapy (2020)

Article

The H2BG53D oncohistone directly upregulates ANXA3 transcription and enhances cell migration in pancreatic ductal adenocarcinoma

Yi Ching Esther Wan, Jiaxian Liu, Lina Zhu… in Signal Transduction and Targeted Therapy (2020)

Article

ATF3 induction prevents precocious activation of skeletal muscle stem cell by regulating H2B expression

Skeletal muscle stem cells (also called satellite cells, SCs) are important for maintaining muscle tissue homeostasis and damage-induced regeneration. However, it remains poorly understood how SCs enter cell c...

Suyang Zhang, Feng Yang, Yile Huang, Liangqiang He, Yuying Li… in Nature Communications (2023)

Article

Author Correction: ATF3 induction prevents precocious activation of skeletal muscle stem cell by regulating H2B expression

Suyang Zhang, Feng Yang, Yile Huang, Liangqiang He, Yuying Li… in Nature Communications (2023)