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Life Sciences
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Neurosciences
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Article
Joint impact of polygenic risk score and lifestyles on early- and late-onset cardiovascular diseases
Understanding the interactions between genetic risk and lifestyles on different types and age onsets of cardiovascular disease (CVD) risk can help identify individuals for whom lifestyle changes would be benef...
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Open AccessInvestigating the impact of poverty on mental illness in the UK Biobank using Mendelian randomization
It is unclear whether poverty and mental illness are causally related. Using UK Biobank and Psychiatric Genomic Consortium data, we examined evidence of causal links between poverty and nine mental illnesses (...
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Open AccessUsing social and behavioral science to address achievement inequality
Achievement inequality has been on the rise. Globally, students from disadvantaged backgrounds perform worse academically than their peers, even with equal ability. This represents a significant loss of potent...
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Multiplex cerebrospinal fluid proteomics identifies biomarkers for diagnosis and prediction of Alzheimer’s disease
Recent expansion of proteomic coverage opens unparalleled avenues to unveil new biomarkers of Alzheimer’s disease (AD). Among 6,361 cerebrospinal fluid (CSF) proteins analysed from the ADNI database, YWHAG per...
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Open AccessDifferences in spatiotemporal brain network dynamics of Montessori and traditionally schooled students
Across development, experience has a strong impact on the way we think and adapt. School experience affects academic and social-emotional outcomes, yet whether differences in pedagogical experience modulate un...
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Open AccessChrysin-loaded PEGylated liposomes protect against alloxan-induced diabetic neuropathy in rats: the interplay between endoplasmic reticulum stress and autophagy
Diabetic neuropathy (DN) is recognized as a significant complication arising from diabetes mellitus (DM). Pathogenesis of DN is accelerated by endoplasmic reticulum (ER) stress, which inhibits autophagy and co...
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Open AccessAuthor Correction: Self-administered mindfulness interventions reduce stress in a large, randomized controlled multi-site study
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Author Correction: Comparing experience- and description-based economic preferences across 11 countries
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Open AccessModulating social learning-induced evaluation updating during human sleep
People often change their evaluations upon learning about their peers’ evaluations, i.e., social learning. Given sleep’s vital role in consolidating daytime experiences, sleep may facilitate social learning, t...
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Open AccessThe impact of premature birth on auditory-visual processes in very preterm schoolchildren
Interactions between stimuli from different sensory modalities and their integration are central to daily life, contributing to improved perception. Being born prematurely and the subsequent hospitalization ca...
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Open AccessLead and calcium crosstalk tempted acrosome damage and hyperpolarization of spermatozoa: signaling and ultra-structural evidences
Exposure of humans and animals to heavy metals is increasing day-by-day; thus, lead even today remains of significant public health concern. According to CDC, blood lead reference value (BLRV) ranges from 3.5 ...
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Open AccessPrincipled distillation of UK Biobank phenotype data reveals underlying structure in human variation
Data within biobanks capture broad yet detailed indices of human variation, but biobank-wide insights can be difficult to extract due to complexity and scale. Here, using large-scale factor analysis, we distil...
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I want universities to put breastfeeding on their gender pay gap agenda
Unsupportive university policies force parents to make choices about how to feed their baby. Ernestine Gheyoh Ndzi, an expert in employment law and advocate for parental rights in the UK, tells us why this nee...
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Why scientific integrity matters now more than ever
This year, 49% of the world will go to the polls. Political support for science-informed policy is not a given. Maria Caffrey, a whistleblower who defended scientific integrity under the Trump administration, ...
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All STEM students should learn inclusive science communication
Science communication often assumes a ‘deficit’ in knowledge on behalf of the recipient, but this deficit-based approach is inequitable and ineffective. We must train all STEM (science, technology, engineering...
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Author Correction: Standing up for the university
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Identifying behaviour-related and physiological risk factors for suicide attempts in the UK Biobank
Suicide is a global public health challenge, yet considerable uncertainty remains regarding the associations of both behaviour-related and physiological factors with suicide attempts (SA). Here we first estima...
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Open AccessThe seasons within: a theoretical perspective on photoperiodic entrainment and encoding
Circadian clocks are internal timing devices that have evolved as an adaption to the omnipresent natural 24 h rhythmicity of daylight intensity. Properties of the circadian system are photoperiod dependent. Th...
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Open AccessAvian migration clocks in a changing world
Avian long-distance migration requires refined programming to orchestrate the birds’ movements on annual temporal and continental spatial scales. Programming is particularly important as long-distance movement...
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Twelve thousand years of ritual practice
It is rare to formally identify ethnographically known rituals in the archaeological record that are more than a few hundred years old. David et al. report two buried miniature fireplaces from Cloggs Cave, sou...
