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Article
Modulation of monocyte subtypes in diabetes after non-surgical periodontal treatment
The current study aims to evaluate the effect of non-surgical periodontal treatment on the modulation of monocyte phenotype, in the presence or absence of diabetes.
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Article
Ubiquitin–proteasome system as a target for anticancer treatment—an update
As the ubiquitin–proteasome system (UPS) regulates almost every biological process, the dysregulation or aberrant expression of the UPS components causes many pathological disorders, including cancers. To find...
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Article
Open AccessIdentification of metabolic markers predictive of prediabetes in a Korean population
Prediabetes (PD) is a high-risk state of develo** type 2 diabetes, and cardiovascular and metabolic diseases. Metabolomics-based biomarker studies can provide advanced opportunities for prediction of PD over...
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Article
Open AccessO-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation
O-linked β-N-acetylglucosamine (O-GlcNAc) is a post-translational modification which occurs on the hydroxyl group of serine or threonine residues of nucleocytoplasmic proteins. It has been reported that the prese...
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Article
Topical application of lectin Artin M improves wound healing in defects created in the palatal mucosa: an in vivo study in dogs
Previous studies have shown that topical application of lectin Artin-M accelerates wound healing in the rat oral mucosa. The aim of this study was to evaluate, by means of histology and immunohistochemistry (I...
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Article
Open AccessPrediction of deep vein thrombosis by ultrasonography and D-dimer in Asian patients with ischemic stroke
Deep vein thrombosis (DVT) is an important complication of ischemic stroke, although the incidence of DVT is regarded as being lower in Asian than in non-Asian patients. Here, we investigated the incidence and...
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Article
Fabrication of Lead-free (K0.5Na0.5)1−xAg x NbO3 Ferroelectric Ceramics and Their Dielectric Properties
In this study, lead-free (K0.5Na0.5)1−xAg x NbO3 (x = 0.00, 0.10, 0.15, 0.20, 0.25, and 0.30) ferroelectric ceramics were fabricated using solid-state synthesis without A-site an...
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Article
Erratum to: Journal of the Korean Physical Society, Vol. 71, No. 10
Regrettably, due to a technical error during the production process, there were discrepancies in DOI of the mentioned articles between HTML and PDF files. The DOIs are correct in the PDF files but were incorre...
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Article
Structural and electrical properties of Li-doped ZnO films
Zn1−xLixO films were spin-coated on platinum substrates by using sol-gel method. The XRD pattern demonstrated that the Li doped ZnO films exhibits the hexagonal wurtzite structure. And, the 18.5 ◦ peak was found ...
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Article
Open AccessOn the association analysis of CNV data: a fast and robust family-based association method
Copy number variation (CNV) is known to play an important role in the genetics of complex diseases and several methods have been proposed to detect association of CNV with phenotypes of interest. Statistical m...
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Article
Characterization of human hybrid cell line, F2N78, through a comparison of culture performances and protein qualities
To evaluate the characteristics of a novel human cell line, F2N78, including growth performance, physicochemical properties, and biological activity via direct comparison with CHO cells.
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Article
Identification of putative biomarkers for type 2 diabetes using metabolomics in the Korea Association REsource (KARE) cohort
Type 2 diabetes (T2D) is a multifactorial disease resulting from a complex interaction between environmental and genetic risk factors. Metabolomics provide a logical framework that reflects the functional endp...
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Article
Open AccessA genome-wide association study of copy-number variation identifies putative loci associated with osteoarthritis in Koreans
OA is a complex disease caused by environmental and genetic risk factors. The purpose of this study is to identify candidate copy number variations (CNVs) associated with OA.
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Article
Raman and dielectric spectroscopy in the disordered Pb(Sc1/2Nb1/2)O3 relaxor fabricated by using a one-step mixed oxide method
Complex perovskite Pb(Sc1/2Nb1/2)O3 ceramics were prepared under three different conditions by using the conventional mixed oxide method. Sintering under different conditions resulted in complete formation of the...
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Article
Exome sequencing as a tool for short stature gene discovery: analysis of a Korean family with pseudohypoparathyroidism
A 4 bp deletion in GNAS has known to be the causal mutation for pseudohypoparathyroidism. In this study, we performed sanger sequencing on exons of GNAS and identified the 4 bp causal deletion in Korean family wi...
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Article
Gadd45-induced cell cycle G2/M arrest for improved transient gene expression in Chinese hamster ovary cells
Gadd45 is a p53-regulated protein and is involved in cell cycle arrest in the G2/M phase. In an effort to improve transient gene expression (TGE) in Chinese hamster ovary (CHO) cells, the effect of Gadd45-indu...
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Article
Effect of glucose feeding on the glycosylation quality of antibody produced by a human cell line, F2N78, in fed-batch culture
The human cell line rF2N78 produces an antibody with a high galactosylation ratio which resembles human IgG. However, it has been observed that the aglycosylated antibody starts to appear when glucose is deple...
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Article
Autophagy and its implication in Chinese hamster ovary cell culture
Chinese hamster ovary (CHO) cells, that are widely used for production of therapeutic proteins, are subjected to apoptosis and autophagy under the stresses induced by conditions such as nutrient deprivation, h...
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Article
Electrical response of mixed regions in the Pb(Mg1/3Ta2/3)O3 and the Pb(Mg1/3Nb2/3)O3 complex perovskites
The dielectric properties of the Pb(Mg1/3Ta2/3)O3-Pb(Mg1/3Nb2/3)O3-PbTiO3 ternary systems were examined as a function of temperature. The split (002) or (200) X-ray diffraction patterns were in the 2θ range of 43...
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Article
Effect of culture pH on recombinant antibody production by a new human cell line, F2N78, grown in suspension at 33.0 °C and 37.0 °C
The human host cell line, F2N78, is a new somatic hybrid cell line designed for therapeutic antibody production. To verify its potential as a human host cell line, recombinant F2N78 cells that produce antibody...
