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Article
Open AccessSuicidal ideation in Chinese patients with advanced breast cancer: a multi-center mediation model study
The pathways underpinning suicide ideation (SI) and certain physical and psychological factors in patients with advanced breast cancer remain unclear. This study develops and validates a mediation model that d...
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Article
Open AccessFeasibility of online managing cancer and living meaningfully (CALM) in Chinese patients with metastatic breast cancer: a pilot randomized control trial
Metastatic breast cancer could cause various psychological symptoms. Managing Cancer and Living Meaningfully (CALM) is a brief, manualized psychotherapy that has been validated for advanced cancer patients. We...
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Article
Open AccessPhysical symptoms and anxiety and depression in older patients with advanced cancer in China: a network analysis
Little is understood about the association between psychosomatic symptoms and advanced cancer among older Chinese patients.
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Article
Open AccessAcetylation is required for full activation of the NLRP3 inflammasome
Full activation of the NLRP3 inflammasome needs two sequential signals: a priming signal, followed by a second, assembly signal. Several studies have shown that the two signals trigger post-translational modif...
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Article
Open AccessYAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3
The transcription coactivator YAP plays a vital role in Hippo pathway for organ-size control and tissue homeostasis. Recent studies have demonstrated YAP is closely related to immune disorders and inflammatory...
