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  1. No Access

    Article

    The Natural Compound Cinnamaldehyde is a Novel Activator of Calcium-Activated Chloride Channel

    Calcium-activated chloride channels (CaCCs) play important roles in a multitude of physiological processes, and in many cells types, TMEM16A was identified as the molecular basis of CaCC. Abnormal CaCC functio...

    Yayue Huang, Shuai Guo, Shuxi Ren, Yafei Chen, Yong Zhan… in The Journal of Membrane Biology (2018)

  2. No Access

    Article

    Hydrocinnamic Acid Inhibits the Currents of WT and SQT3 Syndrome-Related Mutants of Kir2.1 Channel

    Gain of function in mutations, D172N and E299V, of Kir2.1 will induce type III short QT syndrome. In our previous work, we had identified that a mixture of traditional Chinese medicine, styrax, is a blocker of...

    Shuxi Ren, Chunli Pang, Yayue Huang, Chengfen **ng… in The Journal of Membrane Biology (2017)