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  1. Article

    A CRISPR toolbox to study virus–host interactions

  2. Viruses are obligate intracellular pathogens that depend on host cellular components for replication.

  3. Genet...

    4. Andreas S. Puschnik, Karim Majzoub, Yaw Shin Ooi… in Nature Reviews Microbiology (2017)

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    Article

    An RNA-centric dissection of host complexes controlling flavivirus infection

    Flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), cause severe human disease. Co-opting cellular factors for viral translation and viral genome replication at the endoplasmic reticulum is a sh...

    Yaw Shin Ooi, Karim Majzoub, Ryan A. Flynn, Miguel A. Mata… in Nature Microbiology (2019)

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    Article

    Enterovirus pathogenesis requires the host methyltransferase SETD3

    Enteroviruses (EVs) comprise a large genus of positive-sense, single-stranded RNA viruses whose members cause a number of important and widespread human diseases, including poliomyelitis, myocarditis, acute fl...

    Jonathan Diep, Yaw Shin Ooi, Alex W. Wilkinson, Christine E. Peters… in Nature Microbiology (2019)