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Article
SlicerPIT: software development and implementation for planning and image-guided therapy in photoimmunotherapy
Photoimmunotherapy is a treatment modality that induces targeted cell death by binding a molecular-targeted drug activated by infrared light to the tumor cells and subsequently illuminating the lesion with inf...
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Article
Low-dose metronomic cisplatin as an antiangiogenic and anti-inflammatory strategy for cancer
Conventional chemotherapy is based on the maximum tolerated dose (MTD) and requires treatment-free intervals to restore normal host cells. MTD chemotherapy may induce angiogenesis or immunosuppressive cell inf...
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Article
Open AccessInhibition of stromal biglycan promotes normalization of the tumor microenvironment and enhances chemotherapeutic efficacy
Biglycan is a proteoglycan found in the extracellular matrix. We have previously shown that biglycan is secreted from tumor endothelial cells and induces tumor angiogenesis and metastasis. However, the functio...
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Article
Feasibility of limited resection for peripheral small-sized non-small cell lung cancer: a retrospective single-center-based study
This study aimed to establish new criteria for limited resection of non-small cell lung cancer (NSCLC) based on computed tomography findings and maximum standardized uptake value (SUVmax).
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Chapter
Tumor Blood Vessels as Targets for Cancer Therapy
Tumor growth and metastasis are dependent on angiogenesis, which is the formation of new blood vessels. The newly formed blood vessels around the tumor supply oxygen and nutrients to the tumor, supporting its ...
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Article
Tumor angiogenesis—characteristics of tumor endothelial cells
Tumor blood vessels provide nutrition and oxygen to the tumor, resulting in tumor progression. They also act as gatekeepers, inducing tumor metastasis. Thus, targeting tumor blood vessels is an important stra...