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Selective Autophagy Regulates Innate Immunity Through Cargo Receptor Network

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  1. Article

    Open Access

    5-HT attenuates chronic stress-induced cognitive impairment in mice through intestinal flora disruption

    The microbiota–gut–brain axis plays an important role in the development of depression. The aim of this study was to investigate the effects of 5-HT on cognitive function, learning and memory induced by chroni...

    Junxing Ma, Ran Wang, Yaoxing Chen, Zixu Wang, Yulan Dong in Journal of Neuroinflammation (2023)

  2. Article

    Open Access

    Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation

    Sleep loss is a serious global health concern. Consequences include memory deficits and gastrointestinal dysfunction. Our previous research showed that melatonin can effectively improve cognitive impairment an...

    **ntong Wang, Zixu Wang, **g Cao, Yulan Dong, Yaoxing Chen in Microbiome (2023)

  3. Article

    Open Access

    Autophagy inhibition and reactive oxygen species elimination by acetyl-CoA acetyltransferase 1 through fused in sarcoma protein to promote prostate cancer

    Prostate cancer is a major health issue affecting the male population worldwide, and its etiology remains relatively unknown. As presented on the Gene Expression Profiling Interactive Analysis database, acetyl...

    **gqian Guan, **zi Jiang, Yaoxing Guo, Wenhui Zhao, Ji Li, Yizhuo Li in BMC Cancer (2022)

  4. Article

    Open Access

    Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion

    Brachial plexus avulsion (BPA) physically involves the detachment of spinal nerve roots themselves and the associated spinal cord segment, leading to permanent paralysis of motor function of the upper limb. Ro...

    Yanfeng Huang, **e Zhang, Qionghui Huang, Yaoxing Dou in Inflammation and Regeneration (2022)

  5. Article

    Open Access

    Engineering multi-specific antibodies against HIV-1

    As increasing numbers of broadly neutralizing monoclonal antibodies (mAbs) against HIV-1 enter clinical trials, it is becoming evident that combinations of mAbs are necessary to block infection by the diverse ...

    Neal N. Padte, Jian Yu, Yaoxing Huang, David D. Ho in Retrovirology (2018)

  6. Article

    Open Access

    Heterogeneity of PD-L1 expression in primary tumors and paired lymph node metastases of triple negative breast cancer

    Programmed cell death ligand 1 (PD-L1) is a potential predictive biomarker of the response to anti-PD-L1/anti- programmed cell death 1 (PD-1) therapy in multiple cancers, including triple negative breast cance...

    Ming Li, Anqi Li, Shuling Zhou, Yan Xu, Yaoxing **ao, Rui Bi, Wentao Yang in BMC Cancer (2018)

  7. Article

    Open Access

    Expression of MACC1 and c-Met in human gastric cancer and its clinical significance

    Recent studies have suggested that the metastasis-associated colon cancer1 (MACC1) gene can promote tumor proliferation, invasion and metastasis through an upregulation of c-Met expression. However, its role i...

    Tiankang Guo, **gyu Yang, Jibin Yao, Yongbin Zhang, Mingxu Da in Cancer Cell International (2013)