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Article
Open AccessDownregulation of HNRNPA1 induced neoantigen generation via regulating alternative splicing
Immunotherapies effectively treat human malignancies, but the low response and resistance are major obstacles. Neoantigen is an emerging target for tumor immunotherapy that can enhance anti-tumor immunity and ...
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Article
Open AccessTyrosine hydroxylase inhibits HCC progression by downregulating TGFβ/Smad signaling
The alteration of metabolic processes has been found to have significant impacts on the development of hepatocellular carcinoma (HCC). Nevertheless, the effects of dysfunction of tyrosine metabolism on the dev...
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Article
Dynamic interactive refinement network for camouflaged object detection
Automatically identifying objects similar to the surroundings is a complex and difficult task in real-world scenarios. In addition to the high intrinsic similarity between camouflaged objects and their backgro...
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Article
GFNet: gated fusion network for video saliency prediction
Most of the cutting-edge 3D convolutional-based video saliency prediction models adopt a fully convolutional encoder-decoder architecture, which provides a good spatiotemporal representation of salient regions...
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Article
Depth-guided deep filtering network for efficient single image bokeh rendering
Bokeh effect is usually used to highlight major contents in an image. Limited by the small sensors, cameras on smartphones are less sensitive to the depth information and cannot directly produce bokeh effect a...
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Article
Open AccessMCM2 in human cancer: functions, mechanisms, and clinical significance
Aberrant DNA replication is the main source of genomic instability that leads to tumorigenesis and progression. MCM2, a core subunit of eukaryotic helicase, plays a vital role in DNA replication. The dysfuncti...
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Article
Open AccessmiR-133a targets YES1 to reduce cisplatin resistance in ovarian cancer by regulating cell autophagy
Accumulating evidence has revealed that aberrant microRNA (miRNA) expression can affect the development of chemotherapy drug resistance by modulating the expression of relevant target proteins. Emerging eviden...
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Chapter and Conference Paper
Therapeutic Effects of Corticosteroids for Critical and Severe COVID-19 Patients
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has led to an unprecedented public health, economic, and social crisis worldwide. Since no therapeutic treatment is ye...
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Chapter and Conference Paper
Dynamic Style Transferring and Content Preserving for Domain Generalization
Although convolutional neural networks (CNNs) have shown remarkable ability in different computer vision tasks, they do not cope well with domain shifts. Recent studies show that the domain shift mainly result...
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Chapter and Conference Paper
Retrospective Evaluation of COVID-19 Therapeutics
The pandemic outbreak of COVID-19 created panic all over the world. As therapeutics that can effectively wipe out the virus and terminate transmission are not available, supportive therapeutics are the main cl...
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Chapter and Conference Paper
A Flower Classification Framework Based on Ensemble of CNNs
Currently, the classification of flower species has become a hot topic in the field of image classification. Flower classification belongs to the category of fine image classification, and such images are usua...
