16 Result(s)

Article

Mosaic chromosomal alterations in peripheral blood leukocytes of children in sub-Saharan Africa

In high-income countries, mosaic chromosomal alterations in peripheral blood leukocytes are associated with an elevated risk of adverse health outcomes, including hematologic malignancies. We investigate mosai...

Weiyin Zhou, Anja Fischer, Martin D. Ogwang, Wen Luo… in Nature Communications (2023)

Article

Circulating trans fatty acids are associated with prostate cancer in Ghanaian and American men

The association between fatty acids and prostate cancer remains poorly explored in African-descent populations. Here, we analyze 24 circulating fatty acids in 2934 men, including 1431 prostate cancer cases and...

Tsion Zewdu Minas, Brittany D. Lord, Amy L. Zhang, Julián Candia… in Nature Communications (2023)

Article

Serum proteomics links suppression of tumor immunity to ancestry and lethal prostate cancer

There is evidence that tumor immunobiology and immunotherapy response may differ between African American and European American prostate cancer patients. Here, we determine if men of African descent harbor a u...

Tsion Zewdu Minas, Julián Candia, Tiffany H. Dorsey… in Nature Communications (2022)

Article

Unrecognized human immunodeficiency virus infection and risk factors among elderly medical patients at the Korle Bu teaching hospital, Accra, Ghana

The human immunodeficiency virus (HIV) infection usually infects persons in the reproductive age group (15–49 years), but elderly people are also susceptible. Many people in sub-Saharan Africa including Ghana ...

Andrew A. Adjei, Seth Agyemang… in Tropical Diseases, Travel Medicine and Vac… (2016)

Article

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Although genome-wide association studies have identified over 100 risk loci that explain ∼33% of familial risk for prostate cancer (PrCa), their functional effects on risk remain largely unknown. Here we use g...

Alexander Gusev, Huwenbo Shi, Gleb Kichaev, Mark Pomerantz… in Nature Communications (2016)

Article

Through the lens of the clinician: autopsy services and utilization in a large teaching hospital in Ghana

Declining hospital autopsy rates in many countries have generated considerable concern. The survey determined challenges of the autopsy service in a large Teaching Hospital in Ghana, from the perspective of cl...

Alfred E Yawson, Edem Tette, Yao Tettey in BMC Research Notes (2014)

Article

Erratum to: A genome-wide association study of prostate cancer in West African men

Michael Blaise Cook, Zhaoming Wang, Edward D. Yeboah, Yao Tettey… in Human Genetics (2014)

Article

Cause of death among Ghanaian adolescents in Accra using autopsy data

There is limited data on adolescent mortality particularly from develo** countries with unreliable death registration systems. This calls for the use of other sources of data to ascertain cause of adolescent...

Sally-Ann Ohene, Yao Tettey, Robert Kumoji in BMC Research Notes (2011)

Article

Unexpected elevated alanine aminotransferase, asparte aminotransferase levels and hepatitis E virus infection among persons who work with pigs in accra, ghana

Several studies have suggested that elevated serum alanine aminotransferase (ALT) and asparte aminotransferase (AST) may be markers of hepatitis E virus (HEV) infection. Thus, individuals with elevated ALT and...

Andrew A Adjei, Yao Tettey, John T Aviyase, Clement Adu-Gyamfi… in Virology Journal (2010)

Article

Injury-related mortality among adolescents: findings from a teaching hospital's post mortem data

Injuries are noted to be an important cause of death among adolescents. There is however limited data on the injury related deaths among adolescents in Ghana.

Sally-Ann Ohene, Yao Tettey, Robert Kumoji in BMC Research Notes (2010)

Article

Hepatitis E virus infection is highly prevalent among pregnant women in Accra, Ghana

Hepatitis E virus (HEV) is highly endemic in several African countries with high mortality rate among pregnant women. The prevalence of antibodies to HEV in Ghana is not known. Therefore we evaluated the preva...

Andrew A Adjei, Yao Tettey, John T Aviyase, Clement Adu-Gyamfi… in Virology Journal (2009)

Article

Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children

Plasmodium falciparum can cause a diffuse encephalopathy known as cerebral malaria (CM), a major contributor to malaria associated mortality. Despite treatment, mortality due to CM can be as high as 30% while 10%...

Henry B Armah, Nana O Wilson, Bismark Y Sarfo, Michael D Powell… in Malaria Journal (2007)