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  1. No Access

    Article

    Genetic epidemiology of thalassemia in couples of childbearing age: over 6 years of a thalassemia intervention project

    Shenzhen is one of the most populated metropolises in southern China where thalassemia is highly prevalent. The prevention of thalassemia inheritance is an ambition of child-bearing couples.

    **ujie Zheng, Yantao Bao, Qunyan Wu, Fang Yao, **di Su… in Molecular Biology Reports (2024)

  2. Article

    Correction to: TIP60 recruits SUV39H1 to chromatin to maintain heterochromatin genome stability and resist hydrogen peroxide-induced cytotoxicity

    The original version of this article, published on November 6, 2020, contained a mistake.

    Bo Tu, Yantao Bao, Ming Tang, Qian Zhu, **aopeng Lu… in Genome Instability & Disease (2021)

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  3. No Access

    Article

    TIP60 recruits SUV39H1 to chromatin to maintain heterochromatin genome stability and resist hydrogen peroxide-induced cytotoxicity

    Tat interacting protein 60 (TIP60) is a histone acetyltransferase involved in chromatin remodeling and the DNA damage response. However, the role of TIP60 in maintaining genome stability is poorly understood. ...

    Bo Tu, Yantao Bao, Ming Tang, Qian Zhu, **aopeng Lu… in Genome Instability & Disease (2020)

  4. No Access

    Article

    A specific assay for JmjC domain-containing lysine demethylase and its application to inhibitor screening

    He Wen, Guo Li, Yongcan Chen, Meiting Li, Yafei Lv… in Science China Life Sciences (2019)

  5. Article

    Open Access

    p53 cooperates with SIRT6 to regulate cardiolipin de novo biosynthesis

    The tumor suppressor p53 has critical roles in regulating lipid metabolism, but whether and how p53 regulates cardiolipin (CL) de novo biosynthesis is unknown. Here, we report that p53 physically interacts wit...

    Meiting Li, Tianyun Hou, Tian Gao, **aopeng Lu, Qiaoyan Yang… in Cell Death & Disease (2018)

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  6. Article

    Open Access

    Sei-1 promotes double minute chromosomes formation through activation of the PI3K/Akt/BRCA1-Abraxas pathway and induces double-strand breaks in NIH-3T3 fibroblasts

    Sei-1 is a potential oncogene that plays an important role in promoting genomic instability. Double minute chromosomes (DMs) are hallmarks of gene amplification and contribute to tumorigenesis. Defects in the DNA...

    **ng Tian, Chang Liu, **n Wang, Fei Wang, Liqun Wang, Lu Xu… in Cell Death & Disease (2018)

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