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Article
Open AccessEvaluation of the advantages of robotic versus laparoscopic surgery in elderly patients with colorectal cancer
The incidence of colorectal cancer increases with aging. Curative-intent surgery based on a minimally invasive concept is expected to bring survival benefits to elderly patients (aged over 80 years) with color...
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Article
Open AccessCREPT/RPRD1B promotes tumorigenesis through STAT3-driven gene transcription in a p300-dependent manner
Signal transducer and activator of transcription 3 (STAT3) has been shown to upregulate gene transcription during tumorigenesis. However, how STAT3 initiates transcription remains to be exploited. This study i...
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Article
Open AccessCREPT is required for murine stem cell maintenance during intestinal regeneration
Intestinal stem cells (ISCs) residing in the crypts are critical for the continual self-renewal and rapid recovery of the intestinal epithelium. The regulatory mechanism of ISCs is not fully understood. Here w...
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Article
Open AccessCREPT/RPRD1B associates with Aurora B to regulate Cyclin B1 expression for accelerating the G2/M transition in gastric cancer
Gastric cancer, like most of other cancers, has an uncontrolled cell cycle regulated by cyclins and cyclin-dependent kinases (CDKs). In this study, we reported that gastric cancer cells showed an accelerated G...
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Article
Enhanced bioactivity of osteoblast-like cells on poly(lactic acid)/poly(methyl methacrylate)/nano-hydroxyapatite scaffolds for bone tissue engineering
Bone tissue engineering has great potential but requires an appropriate substrate with good bioactivity. In this study, poly(lactic acid) (PLA)/poly(methyl methacrylate) (PMMA)/nano-hydroxyapatite (n-HA) hybri...
