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    Article

    Identification of a protective Bacteroides strain of alcoholic liver disease and its synergistic effect with pectin

    The depletion of Bacteroides in the gut is closely correlated with the progression of alcoholic liver disease (ALD). This study aimed to identify Bacteroides strains with protective effects against ALD and evalua...

    Qiangqiang Wang, Yating Li, Longxian Lv in Applied Microbiology and Biotechnology (2022)

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    Open Access

    Improved functionality of Ligilactobacillus salivarius Li01 in alleviating colonic inflammation by layer-by-layer microencapsulation

    The low viability during gastrointestinal transit and poor mucoadhesion considerably limits the effectiveness of Ligilactobacillus salivarius Li01 (Li01) in regulating gut microbiota and alleviating inflammatory ...

    Mingfei Yao, Yanmeng Lu, Ting Zhang, Jiaojiao **e in npj Biofilms and Microbiomes (2021)

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    Article

    Administration of Bifidobacterium bifidum CGMCC 15068 modulates gut microbiota and metabolome in azoxymethane (AOM)/dextran sulphate sodium (DSS)-induced colitis-associated colon cancer (CAC) in mice

    The gut microbiota plays an important role in colorectal cancer (CRC), and the use of probiotics might be a promising intervention method. The aim of our study was to investigate the beneficial effect of Bifidoba...

    Qing Wang, Kaicen Wang, Wenrui Wu, Longxian Lv in Applied Microbiology and Biotechnology (2020)

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    Article

    Lactobacillus helveticus R0052 alleviates liver injury by modulating gut microbiome and metabolome in d-galactosamine-treated rats

    The liver is an important digestive gland, and acute liver failure results in high mortality. Probiotics are considered potential adjuvant therapies for liver disease. This study aimed to investigate the benef...

    Qiangqiang Wang, Longxian Lv, Huiyong Jiang in Applied Microbiology and Biotechnology (2019)

  5. No Access

    Article

    Lentivirus-Mediated RNA Interference Targeting RhoA Slacks the Migration, Proliferation, and Myelin Formation of Schwann Cells

    RhoA, a member of Rho GTPases family, is known to play an important role in remodeling actin cytoskeleton. During the development of the peripheral nervous system (PNS), Schwann cells undergo proliferation, mi...

    **kun Wen, Changhui Qian, Mengjie Pan, **anghai Wang in Molecular Neurobiology (2017)