14 Result(s)

Article

A combined encoder–transformer–decoder network for volumetric segmentation of adrenal tumors

The morphology of the adrenal tumor and the clinical statistics of the adrenal tumor area are two crucial diagnostic and differential diagnostic features, indicating precise tumor segmentation is essential. Th...

Li** Wang, Mingtao Ye, Yanjie Lu, Qicang Qiu… in BioMedical Engineering OnLine (2023)

Article

Cullin-associated and neddylation-dissociated protein 1 (CAND1) alleviates NAFLD by reducing ubiquitinated degradation of ACAA2

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder with high morbidity and mortality. The current study aims to explore the role of Cullin-associated and neddylation-dissociated protein...

**ang Huang, **n Liu, **ngda Li, Yang Zhang, Jianjun Gao… in Nature Communications (2023)

Article

Cytoplasmic sequestration of p53 by lncRNA-CIRPILalleviates myocardial ischemia/reperfusion injury

Myocardial ischemia/reperfusion (MI/R) injury is a pathological process that seriously affects the health of patients with coronary artery disease. Long non-coding RNAs (lncRNAs) represents a new class of regu...

Yuan Jiang, Ying Yang, Yang Zhang, Jiqin Yang, Man-man Zhang… in Communications Biology (2022)

Article

The long noncoding RNA lncCIRBIL disrupts the nuclear translocation of Bclaf1 alleviating cardiac ischemia–reperfusion injury

Cardiac ischemia–reperfusion (I/R) injury is a pathological process resulting in cardiomyocyte death. The present study aims to evaluate the role of the long noncoding RNA Cardiac Injury-Related Bclaf1-Inhibit...

Yang Zhang, **aofang Zhang, Benzhi Cai, Ying Li, Yuan Jiang… in Nature Communications (2021)

Article

Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling

Long non-coding RNAs (lncRNAs) have emerged as a new class of gene expression regulators playing key roles in many biological and pathophysiological processes. Here, we identify cardiac conduction regulatory R...

Yong Zhang, Lihua Sun, Lina Xuan, Zhenwei Pan, Xueling Hu… in Nature Communications (2018)

Article

Isoprenaline/β2-AR activates Plexin-A1/VEGFR2 signals via VEGF secretion in gastric cancer cells to promote tumor angiogenesis

The role of stress signals in regulating gastric cancer initiation and progression is not quite clear. It is known that stress signals modulate multiple processes such as immune function, cell migration and an...

Yanjie Lu, Qian Xu, Yanzhen Zuo, Lei Liu, Shaochen Liu, Lei Chen, Kang Wang… in BMC Cancer (2017)

Article

MIAT Is a Pro-fibrotic Long Non-coding RNA Governing Cardiac Fibrosis in Post-infarct Myocardium

A long non-coding RNA (lncRNA), named myocardial infarction associated transcript (MIAT), has been documented to confer risk of myocardial infarction (MI). The aim of this study is to elucidate the pathophysio...

Xuefeng Qu, Yue Du, You Shu, Ming Gao, Fei Sun, Shenjian Luo, Ti Yang… in Scientific Reports (2017)

Article

Reciprocal Changes of Circulating Long Non-Coding RNAs ZFAS1 and CDR1AS Predict Acute Myocardial Infarction

This study sought to evaluate the potential of circulating long non-coding RNAs (lncRNAs) as biomarkers for acute myocardial infarction (AMI). We measured the circulating levels of 15 individual lncRNAs, known...

Ying Zhang, Lihua Sun, Lina Xuan, Zhenwei Pan, Kang Li… in Scientific Reports (2016)

Article

Upregulation of M₃ muscarinic receptor inhibits cardiac hypertrophy induced by angiotensin II

M₃ muscarinic acetylcholine receptor (M₃-mAChR) is stably expressed in the myocardium, but its pathophysiological role remains largely undefined. This study aimed to investigate the role of M₃-mAChR in cardiac hy...

Yan Liu, Shu Wang, Chao Wang, Haoxin Song, Hongmei Han… in Journal of Translational Medicine (2013)

Article

Bioactivity-guided fractionation of the triglyceride-lowering component and in vivo and in vitro evaluation of hypolipidemic effects of Calyx seu Fructus Physalis

In folklore, some people take the decoction of Calyx seu Fructus Physalis (CSFP) for lowering blood lipids. The present study is designed to evaluate the lipid-lowering activities of CSFP, and search for its phar...

Yihui Yang, **anmei Piao, Mingyu Zhang, **aodan Wang… in Lipids in Health and Disease (2012)

Article

Correction: Corrigendum: The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2

Nat. Med. 13, 486–497 (2007); published online 1 April 2007; corrected after print 6 December 2011 In the version of this article initially published, lanes from the original blot shown in Figure 2b (NIZ and I...

Baofeng Yang, Huixian Lin, Jiening **ao, Yanjie Lu, **aobin Luo… in Nature Medicine (2011)

Article

Addendum: The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2

Baofeng Yang, Huixian Lin, Jiening **ao, Yanjie Lu, **aobin Luo… in Nature Medicine (2011)

Article

Overexpression of M₃ Muscarinic Receptor Is a Novel Strategy for Preventing Sudden Cardiac Death in Transgenic Mice

The present study was designed to investigate the cardiac benefits of M₃ muscarinic receptor (M₃-mAChR) overexpression and whether these effects are related to the regulation of the inward rectifying K⁺ channel b...

Yan Liu, Lihua Sun, Zhenwei Pan, Yunlong Bai, Ning Wang, **long Zhao… in Molecular Medicine (2011)

Article

miRNAs at the heart of the matter

Cardiovascular disease is among the main causes of morbidity and mortality in developed countries. The pathological process of the heart is associated with altered expression profile of genes that are importan...

Zhiguo Wang, **oabin Luo, Yanjie Lu, Baofeng Yang in Journal of Molecular Medicine (2008)