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Article
Open AccessRenal denervation restores biomechanics of carotid arteries in a rat model of hypertension
The prevalence of hypertension increases with aging and is associated with increased arterial stiffness. Resistant hypertension is presented when drug treatments fail to regulate a sustained increased blood pr...
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Article
Open AccessProgressive mechanical and structural changes in anterior cerebral arteries with Alzheimer’s disease
Alzheimer's disease (AD) is a neurodegenerative disease and the main cause for dementia. The irreversible neurodegeneration leads to a gradual loss of brain function characterized predominantly by memory loss....
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Article
Contribution of Elastic and Collagen Fibers to the Mechanical Behavior of Bovine Nuchal Ligament
Ligamentum nuchae is a highly elastic tissue commonly used to study the structure and mechanics of elastin. This study combines imaging, mechanical testing, and constitutive modeling to examine the structural org...
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Chapter
Structural and Mechanical Inhomogeneity in Arterial ECM: Implications for Physiology and Disease
The extracellular matrix (ECM) of an artery endows the tissue its load bearing and damage resistance capacities. This chapter presents a review on the complex interplay between the multiscale ECM structural in...
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Article
Mechanical and structural contributions of elastin and collagen fibers to interlamellar bonding in the arterial wall
The artery relies on interlamellar structural components, mainly elastin and collagen fibers, for maintaining its integrity and resisting dissection propagation. In this study, the contribution of arterial ela...
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Chapter
Intrinsic Optical Imaging of ECM Mechanics
This chapter provides a comprehensive introduction to optical imaging in the context of (ECM) mechanics. The goal is to address the critical aspects of optical microscopy so that researchers in the researc...
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Chapter and Conference Paper
Research on the Teaching Model of Experimental Virtualization in Digital Logic and Digital System Design Course
By stating the problems faced by the experiment of digital logic design course in traditional laboratory, the necessity of hardware experiment virtualization is analyzed, and then two virtual experiment method...
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Chapter and Conference Paper
Gathering Ideas by Exploring Bursting into Sparks Through the Cross–To Discuss Interdisciplinary Role in Cultivating Students’ Innovation
With the continuous development of science and technology, intersection of different disciplines has become a new growth point of science and technology innovation. This paper starts with the interdisciplinary...
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Chapter and Conference Paper
Application of Project Management in Undergraduates’ Innovation Experiment Teaching
In view of unique characteristics of the experiment course of low power embedded system design and implementation, the project management theory is introduced into undergraduates’ innovation experiment teachin...
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Chapter and Conference Paper
From Small Scale Guerrilla Warfare to a Wide Range of Army Operations the Development Direction of Software Production and Education
With the great improvement of computer computing power, the requirement of the software can be greatly improved in terms of performance, scale and reliability. From the programming of one or several people, it...
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Article
Online UAV path planning in uncertain and hostile environments
Taking uncertainties of threats and vehicles’ motions and observations into account, the challenge we have to face is how to plan a safe path online in uncertain and dynamic environments. We construct the stat...
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Article
Glycosaminoglycans contribute to extracellular matrix fiber recruitment and arterial wall mechanics
Elastic and collagen fibers are well known to be the major load-bearing extracellular matrix (ECM) components of the arterial wall. Studies of the structural components and mechanics of arterial ECM generally ...
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Article
Multi-scale Modeling of the Cardiovascular System: Disease Development, Progression, and Clinical Intervention
Cardiovascular diseases (CVDs) are the leading cause of death in the western world. With the current development of clinical diagnostics to more accurately measure the extent and specifics of CVDs, a laudable ...
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Article
Characterization of Biaxial Mechanical Behavior of Porcine Aorta under Gradual Elastin Degradation
Arteries are composed of multiple constituents that endow the wall with proper structure and function. Many vascular diseases are associated with prominent mechanical and biological alterations in the wall con...
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Article
Progressive structural and biomechanical changes in elastin degraded aorta
Aortic aneurysm is an important clinical condition characterized by common structural changes such as the degradation of elastin, loss of smooth muscle cells, and increased deposition of fibrillary collagen. W...
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Article
The orthotropic viscoelastic behavior of aortic elastin
In this paper, we studied the viscoelastic behaviors of isolated aortic elastin using combined modeling and experimental approaches. Biaxial stress relaxation and creep experiments were performed to study the ...
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Article
Mechanical and Material Characterization of Bilayer Microcantilever-based IR detectors
Infrared radiation (IR) detection and imaging are of great importance to a variety of military and civilian applications. Microcantilever-based IR detectors have recently gained a lot of interest because of th...
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Article
Suppression of Inelastic Deformation in Multilayer Microcantilevers with Nanoscale Coating
Multilayer microcantilevers present in micro-/nano- electromechanical system (MEMS/NEMS) applications serving passive and active structural roles. The application and commercialization of MEMS devices suffer f...
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Article
An Experimental and Theoretical Study on the Anisotropy of Elastin Network
The mechanical properties of elastin network from bovine thoracic aorta under biaxial tensile loading were studied both experimentally and theoretically. Histology and scanning electron microscopy were perform...
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Article
A Microstructural Hyperelastic Model of Pulmonary Arteries Under Normo- and Hypertensive Conditions
This work represents the first application of a statistical mechanics based microstructural orthotropic hyperelastic model to pulmonary artery mechanics under normotensive and hypertensive conditions. The mode...
