-
Article
Open AccessHigh seismic velocity structures control moderate to strong induced earthquake behaviors by shale gas development
Moderate to strong earthquakes have been induced worldwide by shale gas development, however, it is still unclear what factors control their behaviors. Here we use local seismic networks to reliably determine ...
-
Article
Certification of visinin-like protein-1 (VILIP-1) certified reference material by amino acid-based and sulfur-based liquid chromatography isotope dilution mass spectrometry
As an emerging neurodegenerative disease, Alzheimer’s disease (AD) has become a leading cause of dementia in older adults. Visinin-like protein-1 (VILIP-1) is an increasingly used biomarker for AD besides the ...
-
Article
Open AccessFabrication of multifunctional metal–organic frameworks nanoparticles via layer-by-layer self-assembly to efficiently discover PSD95-nNOS uncouplers for stroke treatment
Disruption of the postsynaptic density protein-95 (PSD95)—neuronal nitric oxide synthase (nNOS) coupling is an effective way to treat ischemic stroke, however, it still faces some challenges, especially lack o...
-
Article
High-Frequency Ground Motion and Source Characteristics of the 2008 Wenchuan and 2013 Lushan, China, Earthquakes
The 2008 MW7.9 Wenchuan and the 2013 MW6.6 Lushan earthquakes, which both occurred on the Longmen Shan thrust belt, show some interesting similarities and differences. Whereas the Wenchuan earthquake entailed a r...
-
Article
Optimization of phage heptapeptide library-screening process for develo** inhibitors of the isocitrate lyase homologue from Mycobacterium tuberculosis
The aims of this study were to screen peptide inhibitors specific for isocitrate lyase (ICL) using a phage peptide library and computer molecular docking and to explore the relevant mechanisms. Using ICL as a ...