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  1. No Access

    Article

    Protective effects of aloperine on neonatal rat primary cultured hippocampal neurons injured by oxygen–glucose deprivation and reperfusion

    Aloperine (ALO), one of the alkaloids isolated from Sophora alopecuroides L., is traditionally used for various diseases including neuronal disorders. This study investigated the protective effects of ALO on neon...

    Ning-Tian Ma, Ru Zhou, Ren-Yuan Chang, Yin-Ju Hao, Lin Ma… in Journal of Natural Medicines (2015)

  2. No Access

    Article

    Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice

    The present study aimed to investigate the potential anti-inflammatory and anti-nociceptive activities of glycyrrhizin (GL) in mice and to explore the possible related mechanisms. Xylene-induced ear edema, car...

    Hong-Ling Wang, Yu-**ang Li, Ya-Ting Niu, Jie Zheng, **g Wu… in Inflammation (2015)

  3. No Access

    Article

    Neuroprotective Effect of Matrine in Mouse Model of Vincristine-Induced Neuropathic Pain

    Chemotherapy drugs such as vincristine (VCR) can cause neuropathic pain, and there is still lack of ideal strategy to treat it. The current study was designed to investigate effect of matrine (MT) on VCR-induc...

    Shuai-Shuai Gong, Yu-**ang Li, Meng-Ting Zhang, Juan Du… in Neurochemical Research (2016)

  4. No Access

    Article

    The Anticonvulsant and Neuroprotective Effects of Oxysophocarpine on Pilocarpine-Induced Convulsions in Adult Male Mice

    Epilepsy is one of the prevalent and major neurological disorders, and approximately one-third of the individuals with epilepsy experience seizures that do not respond well to available medications. We investi...

    Gang Liu, **g Wang, **an-Hua Deng, Peng-Sheng Ma… in Cellular and Molecular Neurobiology (2017)

  5. No Access

    Article

    Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons

    Lycium barbarum polysaccharides (LBP) have been reported to have a wide range of beneficial effects including neuroprotection, anti-aging and anticancer. However, the anti-inflammation me...

    Peng Zhao, Ning-Tian Ma, Ren-Yuan Chang, Yu-**ang Li… in Cell and Tissue Research (2017)

  6. No Access

    Article

    Neuroprotective Effects of Lycium barbarum Polysaccharide on Focal Cerebral Ischemic Injury in Mice

    Increasing evidence demonstrates inflammation contributes to neuronal death following cerebral ischemia. Lycium barbarum polysaccharide (LBP) has been reported to prevent scopolamine-induced cognitive and memory ...

    Peng Zhao, Ru Zhou, **ao-Yun Zhu, Gang Liu, Yu-** Zhao… in Neurochemical Research (2017)

  7. No Access

    Article

    Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats

    Neonatal hypoxic-ischemic brain damage (HIBD) is one of the leading causes of neonatal mortality and permanent neurological disability worldwide and the effective treatment strategies are not yet available. It...

    Wei Wu, Wei Wei, Min Lu, **aoyun Zhu, Ning Liu, Yang Niu, Tao Sun… in Neurochemical Research (2017)

  8. No Access

    Article

    Anticonvulsant Effect of Swertiamarin Against Pilocarpine-Induced Seizures in Adult Male Mice

    Epilepsy is one of the common and major neurological disorders, approximately a third of the individuals with epilepsy suffer from seizures and not able to successfully respond to available medications. Curren...

    **an-Hua Deng, **ao Zhang, **g Wang, Peng-Sheng Ma, Lin Ma… in Neurochemical Research (2017)

  9. No Access

    Article

    Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen–Glucose Deprivation and Reperfusion

    Oxysophocarpine (OSC), an alkaloid isolated from Sophora flavescens Ait, has been traditionally used as a medicinal agent based on the observed pharmacological effects. In this study, the direct effect of OSC ...

    Peng Zhao, Ren-Yuan Chang, Ning Liu, **g Wang… in Cellular and Molecular Neurobiology (2018)

  10. No Access

    Article

    Neuroprotection of Cytisine Against Cerebral Ischemia–Reperfusion Injury in Mice by Regulating NR2B-ERK/CREB Signal Pathway

    The aim of the study was to elucidate the therapeutic effects of Cytisine (CYT) on cerebral ischemia–reperfusion injury in mice. Male ICR mice were pretreated with reagents (drug), and then subjected to 2 h fo...

    Peng Zhao, Jia-Mei Yang, Yong-Sheng Wang, Yin-Ju Hao, Yu-**ang Li… in Neurochemical Research (2018)

  11. No Access

    Article

    Lycium barbarum polysaccharide attenuates diabetic testicular dysfunction via inhibition of the PI3K/Akt pathway-mediated abnormal autophagy in male mice

    Testicular dysfunction is one of the serious secondary complications in diabetes. Lycium barbarum polysaccharide (LBP) has long been considered to possess a wide range of beneficial properties including antiaging...

    Guang-Jiang Shi, Jie Zheng, **ao-Xu Han, Ya-** Jiang… in Cell and Tissue Research (2018)

  12. No Access

    Article

    Piperine-Loaded Glycyrrhizic Acid- and PLGA-Based Nanoparticles Modified with Transferrin for Antitumor

    The purpose of this study was to enhance the antitumor effect of piperine by constructing the nanoparticles modified with transferrin (Tf-PIP-NPs) and evaluating their efficacy in vitro and in vivo. The Tf-PIP-NP...

    Shuang Li, Jueshuo Guo, Zonghua Tian, **g Chen, Guo**g Gou, Yang Niu… in AAPS PharmSciTech (2021)

  13. Article

    Correction to: Piperine-Loaded Glycyrrhizic Acid- and PLGA-Based Nanoparticles Modified with Transferrin for Antitumor

    Shuang Li, Jueshuo Guo, Zonghua Tian, **g Chen, Guo**g Gou, Yang Niu… in AAPS PharmSciTech (2021)

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