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Open AccessMultimodal cell atlas of the ageing human skeletal muscle
Muscle atrophy and functional decline (sarcopenia) are common manifestations of frailty and are critical contributors to morbidity and mortality in older people1. Deciphering the molecular mechanisms underlying s...
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Article
Open AccessIdentification and experimental validation of autophagy-related genes in abdominal aortic aneurysm
Autophagy plays essential roles in abdominal aortic aneurysm (AAA) development and progression. The objective of this study was to verify the autophagy-related genes (ARGs) underlying AAA empirically and using...
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Article
Open AccessWhat is the optimal dose of adipose-derived mesenchymal stem cells treatment for knee osteoarthritis? A conventional and network meta-analysis of randomized controlled trials
Despite increasing clinical investigations underscoring the efficacy and safety of adipose-derived mesenchymal stem cells (AD-MSCs) therapy in knee osteoarthritis (KOA), no article has recently reviewed the ce...
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Article
miRNA Therapy in Laboratory Models of Acute Spinal Cord Injury in Rodents: A Meta-analysis
miRNA therapy is popularly investigated in treating acute spinal cord injury (SCI) and offers a significant prospect for the treatment of acute SCI. We aimed to provide pre-clinical validations of miRNA in the...
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Effects of Racial Differences on Bariatric Surgery Selection
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Individuals Undergoing Bariatric Surgery Ameliorate Hepatic Steatosis: Evidence from NHANES 2015–2018
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Radiomics May Be a New Opportunity for Bariatric Surgery
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Open AccessThe safety of MSC therapy over the past 15 years: a meta-analysis
Despite increasing clinical investigations emphasizing the safety of mesenchymal stem cell (MSC) therapy in different populations with different diseases, no article has recently reviewed the adverse events in...
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Article
Open AccessOpioid doses required for pain management in lung cancer patients with different cholesterol levels: negative correlation between opioid doses and cholesterol levels
Pain management has been considered as significant contributor to broad quality-of-life improvement for cancer patients. Modulating serum cholesterol levels affects analgesia abilities of opioids, important pa...
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Open AccessSerum levels of M-CSF, RANKL and OPG in rats fed with Kashin-Beck disease-affected diet
There were no studies on the macrophage colony-stimulating factor (M-CSF), receptor activator of NF-kappaB ligand (RANKL) and osteoprotegerin (OPG) in the pathogenesis of Kashin-Beck disease (KBD). The objecti...
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Open AccessMagnetic resonance imaging in the tibial epiphyseal growth plate development of Wistar rat
This research aims to investigate magnetic resonance imaging (MRI) in the tibial epiphyseal growth plate development of Wistar rat.
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Allograft ligament transplantation in anterior cruciate ligament reconstruction patients with meniscal tears
It currently remains unclear whether the meniscal repair clinical results were affected by the graft used in anterior cruciate ligament (ACL) reconstruction. This retrospective study designed to evaluate the d...
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In vivo study of porous strontium-doped calcium polyphosphate scaffolds for bone substitute applications
The purpose of this study was to investigate in vivo biocompatibility and osteogenesis as well as degradability of the porous strontium-doped calcium polyphosphate (SCPP) scaffolds as a biomaterial for bone su...