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Article
Study on the mechanism of vitamin E alleviating non-alcoholic fatty liver function based on non-targeted metabolomics analysis in rats
Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome. Vitamin E (VE) has antioxidant properties and can mediate lipid metabolism. Non-targeted metabolomics technology was ...
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Article
Open AccessAn arrayed CRISPR knockout screen identifies genetic regulators of GLUT1 expression
Glucose, a primary fuel source under homeostatic conditions, is transported into cells by membrane transporters such as glucose transporter 1 (GLUT1). Due to its essential role in maintaining energy homeostasi...
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Article
Metabolic variation and oxidative stress response of blue mussels (Mytilus sp.) perturbed by norfloxacin exposure
Antibiotics are currently widely applied in agricultural cultivation, animal husbandry, and medical treatment, but the effects and ecological risks of antibiotics need to be further investigated. Norfloxacin i...
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Article
Modified umbilical cord-blood transplantation for pediatric patients with mucopolysaccharidosis
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Chapter
Ecological Risk Assessment of Emerging Pollutants: Methodology and Application
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Article
Open AccessNuclear receptor ligand screening in an iPSC-derived in vitro blood–brain barrier model identifies new contributors to leptin transport
The hormone leptin exerts its function in the brain to reduce food intake and increase energy expenditure to prevent obesity. However, most obese subjects reflect the resistance to leptin even with elevated se...
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Article
Open AccessIdentification and characterization of a new geminivirus from soybean plants and determination of V2 as a pathogenicity factor and silencing suppressor
Soybean is one of the four major crops in China. The occurrence of viruses in soybean causes significant economic losses.
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Reference Work Entry In depth
Heat Capacity of Ionic Liquids
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Article
Open AccessIdentification and functional analyses of host factors interacting with the 17-kDa protein of Barley yellow dwarf virus-GAV
Barley yellow dwarf viruses (BYDVs) cause significant economic losses on barley, wheat, and oats worldwide. 17-kDa protein (17K) of BYDVs plays a key role in viral infection in plants, whereas the underlying r...
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Article
Clustering-based privacy preserving anonymity approach for table data sharing
Government data sharing can effectively improve the efficiency and quality of government services and enhance the ability of providing government services. However, data sharing may bring the risk of citizen p...
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Article
Open AccessAdvances in blood–brain barrier modeling in microphysiological systems highlight critical differences in opioid transport due to cortisol exposure
The United States faces a national crisis involving opioid medications, where currently more than 130 people die every day. To combat this epidemic, a better understanding is needed of how opioids penetrate in...
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Living Reference Work Entry In depth
Heat Capacity of Ionic Liquids
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Article
Norm index for predicting the rate constants of organic contaminants oxygenated with sulfate radical
The degradation of organic contaminants in aquatic systems has raised immense attention worldwide, and the second-order rate constant (kSO4.−\( {k}_{{\mathrm{SO}}_4^{.-}} \)) of water pollutants oxidized by sulfa...
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Article
Open AccessIdentification of cucurbit chlorotic yellows virus P4.9 as a possible movement protein
Cucurbit chlorotic yellows virus (CCYV) is a bipartite cucurbit-infecting crinivirus within the family Closteroviridae. The crinivirus genome varies among genera. P4.9 is the first protein encoded by CCYV RNA2. P...
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Protocol
In Vitro Blood-Brain Barrier Functional Assays in a Human iPSC-Based Model
The blood-brain barrier (BBB) is a key biological interface that controls trafficking between the bloodstream and brain to maintain neural homeostasis. To carry out this role, the BBB exhibits several speciali...
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Article
Two proteins of Cucurbit chlorotic yellows virus, P59 and P9, are self-interacting
The yeast two-hybrid (Y2H) assay, a powerful tool for identifying protein–protein interactions, has been widely used to study viral protein interactions and to elucidate the functions of viral proteins. In th...
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Article
Spatial variability and temporal trends of HCH and DDT in soils around Bei**g Guanting Reservoir, China
Spatial variability and temporal trends in concentrations of the organochlorine pesticides (OCPs), hexachlorocyclohexane (HCH) and dichlorodiphenyltrichloroethane (DDT), in surface soils around Bei**g Guantin...
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Article
Factors affecting HCH and DDT in soils around watersheds of Bei**g reservoirs, China
The factors that influence the dynamics of hexachlorocyclohexane (HCH) and dichlorodiphenyltrichloroethane (DDT) in soils around the watersheds of Bei**g reservoirs were examined. Compared with other studies ...
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Article
Distribution and sources of mercury in soils from former industrialized urban areas of Bei**g, China
Fifty-seven typical surface soils and 108 deeper soils were collected from five former industrial sites in Bei**g and concentrations of total Hg (ΣHg) as well as pH, total carbon (TC), total nitrogen (TN), to...
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Article
Identification of sources of elevated concentrations of polycyclic aromatic hydrocarbons in an industrial area in Tian**, China
The concentrations of 16 polycyclic aromatic hydrocarbons (PAHs) were determined by gas chromatography equipped with a mass spectrometry detector in 105 topsoil samples from an industrial area around Bohai Bay...