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Article
Levomilnacipran Improves Lipopolysaccharide-Induced Dysregulation of Synaptic Plasticity and Depression-Like Behaviors via Activating BDNF/TrkB Mediated PI3K/Akt/mTOR Signaling Pathway
Depression is a common psychological disease with high morbidity and mortality. Recently, the involvement of synaptic plasticity in the pathogenesis of depression has shed light on the direction of develo** ...
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Article
Open AccessThe mitochondria-related gene risk mode revealed p66Shc as a prognostic mitochondria-related gene of glioblastoma
Numerous studies have highlighted the pivotal role of mitochondria-related genes (MRGs) in the initiation and progression of glioblastoma (GBM). However, the specific contributions of MRGs coding proteins to G...
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Article
Open AccessCarotid-cavernous fistula(CCF) presenting as paroxysmal painful ophthalmoplegia
Painful ophthalmoplegia can be caused by various etiologies, and broad differential diagnosis is needed. Carotid-cavernous fistula (CCF) is a rare cause of painful ophthalmoplegia, and early diagnosis is quite...
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Article
Open AccessPharmacokinetic study of single- and multiple-dosing with metolazone tablets in healthy Chinese population
Metolazone is a diuretic, saluretic and antihypertensive chemical compound from the quinazoline category that possesses medicinal features similar to those of other thiazide diuretic drugs. However, the pharma...