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  1. Article

    Open Access

    MAPK14 over-expression is a transcriptomic feature of polycythemia vera and correlates with adverse clinical outcomes

    The transcriptomic signature has not been fully elucidated in PV, as well as mRNA markers for clinical variables (thrombosis, leukemic transformation, survival, etc.). We attempted to reveal and validate cruci...

    Chao Guo, Ya-yue Gao, Qian-qian Ju, Min Wang in Journal of Translational Medicine (2021)

  2. Article

    Open Access

    The landscape of gene co-expression modules correlating with prognostic genetic abnormalities in AML

    The heterogenous cytogenetic and molecular variations were harbored by AML patients, some of which are related with AML pathogenesis and clinical outcomes. We aimed to uncover the intrinsic expression profiles...

    Chao Guo, Ya-yue Gao, Qian-qian Ju, Chun-xia Zhang in Journal of Translational Medicine (2021)

  3. Article

    Open Access

    HELQ and EGR3 expression correlate with IGHV mutation status and prognosis in chronic lymphocytic leukemia

    IGHV mutation status is a crucial prognostic biomarker for CLL. In the present study, we investigated the transcriptomic signatures associating with IGHV mutation status and CLL prognosis.

    Chao Guo, Ya-yue Gao, Qian-qian Ju, Chun-xia Zhang in Journal of Translational Medicine (2021)

  4. Article

    Open Access

    LINC00649 underexpression is an adverse prognostic marker in acute myeloid leukemia

    Long noncoding RNAs (lncRNA) play a role in leukemogenesis, maintenance, development, and therapeutic resistance of AML. While few studies have focused on the prognostic significance of LINC00649 in AML, which...

    Chao Guo, Ya-yue Gao, Qian-qian Ju, Chun-xia Zhang, Ming Gong, Zhen-ling Li in BMC Cancer (2020)

  5. Article

    Open Access

    Overexpression of HOXA10 is associated with unfavorable prognosis of acute myeloid leukemia

    HOXA family genes were crucial transcription factors involving cell proliferation and apoptosis. While few studies have focused on HOXA10 in AML. We aimed to investigate the prognostic significance of HOXA10.

    Chao Guo, Qian-qian Ju, Chun-xia Zhang, Ming Gong, Zhen-ling Li, Ya-yue Gao in BMC Cancer (2020)

  6. Article

    The effects of the binocular disparity differences between targets and maskers on visual search

    A visual search for targets is facilitated when the target objects are on a different depth plane than other masking objects cluttering the scene. The ability of observers to determine whether one of four lett...

    Ya-Yue Gao, Bruce Schneider, Liang Li in Attention, Perception, & Psychophysics (2017)