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  1. Article

    Efficacy of afatinib, an irreversible ErbB family blocker, in the treatment of intracerebral metastases of non-small cell lung cancer in mice

    Few effective therapeutic options are currently available for the treatment of non-small cell lung cancer (NSCLC) with brain metastases (BM). Recent evidence shows that NSCLC patients with BMs respond well to ...

    Shi-rong Zhang, Lu-cheng Zhu, Yan-** Jiang, **g Zhang… in Acta Pharmacologica Sinica (2017)

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  2. Article

    Capilliposide from Lysimachia capillipes inhibits AKT activation and restores gefitinib sensitivity in human non-small cell lung cancer cells with acquired gefitinib resistance

    Most gefitinib-treated patients with non-small cell lung cancer (NSCLC) would eventually develop resistance. Lysimachia capillipes (LC) capilliposide extracts from LC Hemsl. show both in vitro and in vivo anti-ca...

    Shi-rong Zhang, Ya-si Xu, Er **, Lu-cheng Zhu, Bing **a… in Acta Pharmacologica Sinica (2017)

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  3. Article

    S-allylcysteine, a garlic derivative, suppresses proliferation and induces apoptosis in human ovarian cancer cells in vitro

    To investigate the effects of S-allylcysteine (SAC), a water-soluble garlic derivative, on human ovarian cancer cells in vitro.

    Ya-si Xu, Jian-guo Feng, Dan Zhang, Bo Zhang, Min Luo, Dan Su… in Acta Pharmacologica Sinica (2014)

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