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Article
124I-labeled anti-CD147 antibody for noninvasive detection of CD147-positive pan-cancers: construction and preclinical studies
Extracellular matrix metalloproteinase inducer CD147 is a glycoprotein on the cell surface. There is minimal expression of CD147 in normal epithelial and fetal tissues, but it is highly expressed in a number o...
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Article
Open AccessTargeting NR1D1 in organ injury: challenges and prospects
Nuclear receptor subfamily 1, group D, member 1 (NR1D1, also known as REV-ERBα) belongs to the nuclear receptor (NR) family, and is a heme-binding component of the circadian clock that consolidates circadian o...
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Article
Open AccessDevelopment and evaluation of serological screening based on one dried plasma spot for HIV, syphilis, and HCV
In the effort to prevent and control HIV/AIDS, China has established a national sentinel surveillance system. However, some sentinel sites face limitations in environmental resources and accessibility, prompti...
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Article
Parameter Study on How the Cervical Disc Degeneration Affects the Segmental Instantaneous Centre of Rotation
Four degenerated models (anterior osteophyte enlargement, intervertebral disc height loss, endplates curvature flattening, and degeneration of the disc material properties) were established by appropriately mo...
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Article
Open AccessEffects of osteoporosis on the biomechanics of various supplemental fixations co-applied with oblique lumbar interbody fusion (OLIF): a finite element analysis
Oblique lumbar interbody fusion (OLIF) is an important surgical modality for the treatment of degenerative lumbar spine disease. Various supplemental fixations can be co-applied with OLIF, increasing OLIF stab...
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Article
68Ga-labeled ODAP-Urea-based PSMA agents in prostate cancer: first-in-human imaging of an optimized agent
Prostate-specific membrane antigen (PSMA) is a promising target for prostate cancer imaging and therapy. The most commonly used scaffold incorporates a glutamate-urea (Glu-Urea) function. We recently developed...
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Article
Production of ectoine through a combined process that uses both growing and resting cells of Halomonas salina DSM 5928T
Using ectoine-excreting strain Halomonas salina DSM 5928T, we developed a new process for high-efficiency production of ectoine, which involved a combined process of batch fermentation by growing cells and produc...
