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Article
Han family with essential tremor caused by the P421L variant of the TENM4 gene in China
Essential tremor (ET) is an autosomal dominant inheritance disorder. Mutations in fusion sarcoma (FUS), mitochondrial serine peptidase 2 (HTRA2), teneurin transmembrane protein 4 (TENM4), sortilin1 (SORT1), SCN11...
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Article
Open AccessIdentification and characterization of two SERPINC1 mutations causing congenital antithrombin deficiency
Antithrombin (AT) is the main physiological anticoagulant involved in hemostasis. Hereditary AT deficiency is a rare autosomal dominant thrombotic disease mainly caused by mutations in SERPINC1, which was usually...
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Chapter
Pathogenic Mechanism of Drug-Resistant Pulmonary Tuberculosis and Its Diagnosis
Pulmonary tuberculosis is one of the main infectious respiratory diseases endangering human health. In comparison with drug-susceptible pulmonary tuberculosis once controlled in developed countries due to the ...
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Article
hUC-MSCs: evaluation of acute and long-term routine toxicity testing in mice and rats
Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are present in human umbilical connective tissue and can differentiate into various cell types. Our previous studies have proved that hUC-MSCs do ...
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Article
Open AccessA thrombophilia family with protein S deficiency due to protein translation disorders caused by a Leu607Ser heterozygous mutation in PROS1
Protein S deficiency (PSD) is an autosomal dominant hereditary disease. In 1984, familial PSD was reported to be prone to recurrent thrombosis. Follow-up studies have shown that heterozygous protein S (PROS1) mut...
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Article
Simultaneous Estimation of Multiple Conditional Regression Quantiles
In this article, we put forward a new approach to estimate multiple conditional regression quantiles simultaneously. Unlike the double summation method in most of the literatures, our proposed model allows con...
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Article
Open AccessRegulation of focal adhesion turnover in SDF-1α-stimulated migration of mesenchymal stem cells in neural differentiation
Directed migration of the transplanted mesenchymal stem cells (MSCs) to the lesion sites plays a pivotal role in the efficacy of cell-based therapy. Our previous study demonstrates that MSCs under varying neur...
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Article
Neural Differentiation of Mesenchymal Stem Cells Influences Their Chemotactic Responses to Stromal Cell-Derived Factor-1α
Mesenchymal stem cells (MSCs) are proposed as a promising source for cell-based therapies in neural disease. Although increasing numbers of studies have been devoted to the delineation of factors involved in t...
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Chapter and Conference Paper
Research on Building Family Networks Based on Bootstrap** and Coreference Resolution
Personal Family Network is an important component of social networks, therefore, it is of great importance of how to extract personal family relationships. We propose a novel method to construct personal famil...
