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  1. Article

    Open Access

    S1PR1 regulates ovarian cancer cell senescence through the PDK1-LATS1/2-YAP pathway

    Cell senescence deters the activation of various oncogenes. Induction of senescence is, therefore, a potentially effective strategy to interfere with vital processes in tumor cells. Sphingosine-1-phosphate rec...

    Yi-** Tao, Heng-Yan Zhu, Qian-Yuan Shi, Cai-**a Wang, Yu-**n Hua, Han-Yin Hu in Oncogene (2023)

  2. Article

    Open Access

    Tanshinone IIA alleviates brain damage in a mouse model of neuromyelitis optica spectrum disorder by inducing neutrophil apoptosis

    Neuromyelitis optica spectrum disorder (NMOSD), an autoimmune astrocytopathic disease associated with the anti-aquaporin-4 (AQP4) antibody, is characterized by extensive necrotic lesions primarily located on t...

    Ye Gong, Ya-ling Zhang, Zhen Wang, Huan-huan Song in Journal of Neuroinflammation (2020)

  3. Article

    Open Access

    Effects of 1,8-cineole on neuropathic pain mediated by P2X2 receptor in the spinal cord dorsal horn

    As an intractable health threat, neuropathic pain is now a key problem in clinical therapy, which can be caused by lesions affecting the peripheral nervous systems. 1,8-cineole is a natural monoterpene cyclic ...

    **ao-bo Zheng, Ya-ling Zhang, Qing Li, Yi-guo Liu, **ang-dong Wang in Scientific Reports (2019)

  4. No Access

    Article

    Biosensor of alkaline phosphatase based on non-fluorescent FRET of Eu3+-doped oxide nanoparticles and phosphorylated peptide labeled with cyanine dye

    Dephosphorylation of biomolecules under the catalysis of alkaline phosphatase (ALP) is a critical physiological process. Abnormal levels of ALP activity have been associated with a number of diseases; thus, a ...

    Fan Shi Li, Ya Ling Zhang, **a Bing Li in Analytical and Bioanalytical Chemistry (2017)

  5. No Access

    Article

    Microwave-assisted Synthesis and antifungal activity of coumarin[8,7-e][1,3]oxazine derivatives

    The synthesis of novel coumarin[8,7-e][1,3]oxazine derivatives through a microwave-assisted three-component one-pot Mannich reaction is described in this study. All the target compounds were evaluated in vitro fo...

    Ming-Zhi Zhang, Rong-Rong Zhang, Wen-Zheng Yin, **ang Yu in Molecular Diversity (2016)

  6. No Access

    Article

    First-Principles Study the Electronic and Thermodynamic Properties for CoBi3 Superconductor

    The electronic, elastic, and thermodynamic properties of CoBi3 superconductor are investigated by means of first-principles calculations along with the quasi-harmonic Debye model. Our results reveal that the calc...

    **ao-** Wei, You-He Zhou, Ya-Ling Zhang in Journal of Superconductivity and Novel Mag… (2016)

  7. No Access

    Article

    SYNTHESIS BIODISTRIBUTION AND QSAR STUDIES OF FIVE Tc-99M LABELED NOVEL N3S PSEUDO-PEPTIDE COMPLEXES

    Five novel N3S pseudo-peptide chelators derived from mercaptoacetic acid have been synthesized and characterized based on the spectroscopic data. All the chelators were labeled with Technicium-99m to evaluate ...

    Hua-bei Zhang, Hai-hong Ye, Ya-ling Zhang, Xuefang Zheng in Medicinal Chemistry Research (2005)