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Open AccessPhenotypic characterisation of regulatory T cells in patients with gestational diabetes mellitus
Gestational diabetes mellitus (GDM) is a common complication that occurs during pregnancy. Emerging evidence suggests that immune abnormalities play a pivotal role in the development of GDM. Specifically, regu...
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Article
Open AccessGDF11 slows excitatory neuronal senescence and brain ageing by repressing p21
As a major neuron type in the brain, the excitatory neuron (EN) regulates the lifespan in C. elegans. How the EN acquires senescence, however, is unknown. Here, we show that growth differentiation factor 11 (G...
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Article
Open AccessDistribution characteristics of organic carbon (nitrogen) content, cation exchange capacity, and specific surface area in different soil particle sizes
Understanding the distribution of soil organic carbon and nitrogen (OC(N)) content, cation exchange capacity (CEC), and specific surface area (SSA) in different soil particle sizes is crucial for studying soil...
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Article
Open AccessDiversity and dynamics of bacteria at the Chrysomya megacephala pupal stage revealed by third-generation sequencing
Characterization of the microbial community is essential for understanding the symbiotic relationships between microbes and host insects. Chrysomya megacephala is a vital resource, a forensic insect, a pollinator...
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Article
Open AccessThe Prognostic Value of Deficient Mismatch Repair in Stage II–IVa Nasopharyngeal Carcinoma in the Era of IMRT
In the era of intensity-modulated radiotherapy (IMRT), it is important to analyse the prognostic value of deficient mismatch repair (dMMR) in nasopharyngeal carcinoma (NPC). In this study, in pretreatment biop...
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Article
Open AccessCNN3 acts as a potential oncogene in cervical cancer by affecting RPLP1 mRNA expression
The prognosis of advanced stage cervical cancer is poorer due to cancer invasion and metastasis. Exploring new factors and signalling pathways associated with invasiveness and metastasis would help to identify...
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Article
Open AccessTemporal patterns of cotton Fusarium and Verticillium wilt in Jiangsu coastal areas of China
Cotton diseases caused by soil-borne pathogenic fungi present a major constraint to cotton production not only in China but also worldwide. A long-term field inventory was made of the prevalence of Fusarium an...
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Article
Open AccessLeukocytic Toll-Like Receptor 2 Deficiency Preserves Cardiac Function And Reduces Fibrosis In Sustained Pressure Overload
An involement of Toll-like receptor 2 (TLR2) has been established in cardiac dysfunction after acute myocardial infarction; however, its role in chronic pressure overload is unclear. We sought to evaluate the ...
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Article
Open AccessReproductive switching analysis of Daphnia similoides between sexual female and parthenogenetic female by transcriptome comparison
The water flea Daphnia are planktonic crustaceans commonly found in freshwater environment that can switch their reproduction mode from parthenogenesis to sexual reproduction to adapt to the external environment....
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Open AccessIdentification and tissue expression profile of genes from three chemoreceptor families in an urban pest, Periplaneta americana
Periplaneta americana is a notorious urban pest prevalent in human habitats; very little is known about its chemosensory mechanism. Employing the advanced next-generation sequencing technique, in the present stud...
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Open AccessLarge number of putative chemoreception and pheromone biosynthesis genes revealed by analyzing transcriptome from ovipositor-pheromone glands of Chilo suppressalis
The chemoreception role of moth ovipositor has long been suggested, but its molecular mechanism is mostly unknown. By transcriptomic analysis of the female ovipositor-pheromone glands (OV-PG) of Chilo suppressali...