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  1. No Access

    Article

    A targetable HB-EGF–CITED4 axis controls oncogenesis in lung cancer

    Aberrant epidermal growth factor (EGF) receptor (EGFR) signaling contributes to neoplastic initiation and progression in lung. Mutated EGFR has become as an important therapeutic target in lung cancer, whereas...

    C-H Hsieh, Y-T Chou, M-H Kuo, H-P Tsai, J-L Chang, C-W Wu in Oncogene (2017)

  2. No Access

    Article

    Protein tyrosine phosphatase PTPN3 inhibits lung cancer cell proliferation and migration by promoting EGFR endocytic degradation

    Epidermal growth factor receptor (EGFR) regulates multiple signaling cascades essential for cell proliferation, growth and differentiation. Using a genetic approach, we found that Drosophila FERM and PDZ domain-c...

    M-Y Li, P-L Lai, Y-T Chou, A-P Chi, Y-Z Mi, K-H Khoo, G-D Chang, C-W Wu… in Oncogene (2015)

  3. No Access

    Article

    Cited2 modulates TGF-β-mediated upregulation of MMP9

    Cited (CBP/p300-interacting transactivators with glutamic acid (E)/aspartic acid (D)-rich C-terminal domain) 2, which is a CBP/p300-binding transcription co-activator without typical DNA-binding domains, has been...

    Y-T Chou, H Wang, Y Chen, D Danielpour, Y-C Yang in Oncogene (2006)